DegronMD: protein-targeted degradation, mutation and drug response to degrons
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Degron:
WRADLGEIS
Uniprot ID:
D6RIA3
Source protein:
Uncharacterized protein C4orf54
Source gene:
C4orf54
Class:
DEG_APCC_DBOX_1
Location:
972:980
E3 ligase:
APC,CDC20,FZR1
DEGRON score:
0.9659
ASA_SCORE:
75.7667
COIL:
0.6977
CONS_SCORE:
0.6162
DSS_SCORE:
0.4681
HELIX:
0.1901
FCONS_SCORE:
1.0047
RIG_SCORE:
0.7513
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with C4orf54 mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of WRADLGEIS
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
D6RIA3
Uncharacterized protein C4orf54
DEG_APCC_DBOX_1
972:980
WRADLGEIS
APC,CDC20,FZR1
0.9659
More...