DegronMD - A0JLT2(MED19)

MED19

Please click HERE for better display.

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.T184I	DO233210	GACA	ICGC	PPETPSDS	DEG_SCF_FBW7_1	189:196	Mutation rewiring degron network	0.1944
p.Q181R	DO228357	LICA	ICGC	PPETPSDS	DEG_SCF_FBW7_1	189:196	Mutation rewiring degron network	0.1111
p.R244C	DO33084	PACA	ICGC	SLR	DEG_APCC_TPR_1	242:244	Mutation altering degron motif	0.8301
p.D195G	DO35442	PACA	ICGC	PPETPSDS	DEG_SCF_FBW7_1	189:196	Mutation altering degron motif	0.6087
p.K191N	SIDM01016	T-Lymphoblastic Leukemia	GDSC	PPETPSDS	DEG_SCF_FBW7_1	189:196	Mutation altering degron motif	0.6918
p.K191N	Jurkat	haematopoietic and lymphoid tissue	COSMIC	PPETPSDS	DEG_SCF_FBW7_1	189:196	Mutation altering degron motif	0.6918
p.P190T	ACH-002105	Bone Cancer	CCLE	PPETPSDS	DEG_SCF_FBW7_1	189:196	Mutation altering degron motif	0.5919

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc