DegronMD - A6NFK2(GRXCR2)

GRXCR2

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G98D	DO234285	ESAD	ICGC	ISVFRE	LIG_APCC_ABBA_1	85:90	Mutation rewiring degron network	0.1111
p.G98D	DO234285	ESAD	ICGC	RISVFRE	LIG_APCC_ABBAyCdc20_2	84:90	Mutation rewiring degron network	0.1111
p.R84K	DO222908	MELA	ICGC	RISVFRE	LIG_APCC_ABBAyCdc20_2	84:90	Mutation altering degron motif	0.6126
p.P78S	DO218849	SKCA	ICGC	ISVFRE	LIG_APCC_ABBA_1	85:90	Mutation rewiring degron network	0.1389
p.P78S	DO218849	SKCA	ICGC	RISVFRE	LIG_APCC_ABBAyCdc20_2	84:90	Mutation rewiring degron network	0.1667
p.S77F	DO229502	SKCA	ICGC	ISVFRE	LIG_APCC_ABBA_1	85:90	Mutation rewiring degron network	0.1111
p.S77F	DO229502	SKCA	ICGC	RISVFRE	LIG_APCC_ABBAyCdc20_2	84:90	Mutation rewiring degron network	0.1389
p.G98C	SIDM00061	Ovarian Carcinoma	GDSC	ISVFRE	LIG_APCC_ABBA_1	85:90	Mutation rewiring degron network	0.1111
p.G98C	SIDM00061	Ovarian Carcinoma	GDSC	RISVFRE	LIG_APCC_ABBAyCdc20_2	84:90	Mutation rewiring degron network	0.1111
p.G98C	SIDM01095	Rhabdomyosarcoma	GDSC	ISVFRE	LIG_APCC_ABBA_1	85:90	Mutation rewiring degron network	0.1111
p.G98C	SIDM01095	Rhabdomyosarcoma	GDSC	RISVFRE	LIG_APCC_ABBAyCdc20_2	84:90	Mutation rewiring degron network	0.1111

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*NOTE: the Kaplan plots were collected from OncoLnc