DegronMD - A8K979(ERI2)

ERI2

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A541D	TCGA-AA-3492	COAD	TCGA	FTIHEE	LIG_APCC_ABBA_1	550:555	Mutation rewiring degron network	0.0833
p.K552N	DO1094	BRCA	ICGC	FTIHEE	LIG_APCC_ABBA_1	550:555	Mutation altering degron motif	0.6918
p.C578Y	DO51734	COAD	ICGC	VRSSS	DEG_SPOP_SBC_1	565:569	Mutation rewiring degron network	0.0833
p.T574K	DO228946	LICA	ICGC	VRSSS	DEG_SPOP_SBC_1	565:569	Mutation rewiring degron network	0.1944
p.D579E	DO228948	LICA	ICGC	VRSSS	DEG_SPOP_SBC_1	565:569	Mutation rewiring degron network	0.0556
p.T564K	DO229031	LICA	ICGC	VRSSS	DEG_SPOP_SBC_1	565:569	Mutation rewiring degron network	0.3056
p.T564K	DO229031	LICA	ICGC	FTIHEE	LIG_APCC_ABBA_1	550:555	Mutation rewiring degron network	0.0833
p.P560Q	DO43154	UCEC	ICGC	VRSSS	DEG_SPOP_SBC_1	565:569	Mutation rewiring degron network	0.1944
p.P560Q	DO43154	UCEC	ICGC	FTIHEE	LIG_APCC_ABBA_1	550:555	Mutation rewiring degron network	0.1944
p.F544L	DO41133	UCEC	ICGC	FTIHEE	LIG_APCC_ABBA_1	550:555	Mutation rewiring degron network	0.1667
p.P544L	SIDM00529	Breast Carcinoma	GDSC	FTIHEE	LIG_APCC_ABBA_1	550:555	Mutation rewiring degron network	0.1667
p.I577F	K-562	haematopoietic and lymphoid tissue	COSMIC	VRSSS	DEG_SPOP_SBC_1	565:569	Mutation rewiring degron network	0.1111

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*NOTE: the Kaplan plots were collected from OncoLnc