DegronMD - O14798(TNFRSF10C)

TNFRSF10C

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A223T	TCGA-56-8628	LUSC	TCGA	PGTPASS	DEG_SCF_FBW7_1	232:238	Mutation rewiring degron network	0.0833
p.M228I	TCGA-A5-A0G1	UCEC	TCGA	PGTPASS	DEG_SCF_FBW7_1	232:238	Mutation rewiring degron network	0.2222
p.S231I	TCGA-A5-A0G1	UCEC	TCGA	PGTPASS	DEG_SCF_FBW7_1	232:238	Mutation rewiring degron network	0.3056
p.N156S	TCGA-AD-6895	COAD	TCGA	VETPAAE	DEG_SCF_FBW7_2	159:165	Mutation rewiring degron network	0.25
p.F153C	TCGA-D1-A103	UCEC	TCGA	VETPAAE	DEG_SCF_FBW7_2	159:165	Mutation rewiring degron network	0.1667
p.P235L	TCGA-DD-AAVR	LIHC	TCGA	PGTPASS	DEG_SCF_FBW7_1	232:238	Mutation altering degron motif	0.7582
p.S238Y	TCGA-EO-A3B0	UCEC	TCGA	PGTPASS	DEG_SCF_FBW7_1	232:238	Mutation altering degron motif	0.712
p.P172L	TCGA-FW-A3R5	SKCM	TCGA	VETPAAE	DEG_SCF_FBW7_2	159:165	Mutation rewiring degron network	0.1389
p.C243Y	TCGA-XK-AAIW	PRAD	TCGA	PGTPASS	DEG_SCF_FBW7_1	232:238	Mutation rewiring degron network	0.1944
p.V159M	SIDM02039	Colorectal Carcinoma	GDSC	VETPAAE	DEG_SCF_FBW7_2	159:165	Mutation altering degron motif	0.6097
p.G233R	ACH-000036	Brain Cancer	CCLE	PGTPASS	DEG_SCF_FBW7_1	232:238	Mutation altering degron motif	0.6457

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*NOTE: the Kaplan plots were collected from OncoLnc