DegronMD - O75995(SASH3)

SASH3

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P60H	TCGA-DZ-6131	KIRP	TCGA	EDDSGVPTP	DEG_COP1_1	54:62	Mutation altering degron motif	0.7694
p.P60H	TCGA-DZ-6131	KIRP	TCGA	DSGVPT	DEG_SCF_TRCP1_1	56:61	Mutation altering degron motif	0.6583
p.P60H	DO20911	KIRP	ICGC	EDDSGVPTP	DEG_COP1_1	54:62	Mutation altering degron motif	0.7694
p.P60H	DO20911	KIRP	ICGC	DSGVPT	DEG_SCF_TRCP1_1	56:61	Mutation altering degron motif	0.6583
p.P62Q	DO231018	LUSC	ICGC	EDDSGVPTP	DEG_COP1_1	54:62	Mutation altering degron motif	0.7035
p.P62L	DO222702	MELA	ICGC	EDDSGVPTP	DEG_COP1_1	54:62	Mutation altering degron motif	0.6471
p.P62S	SIDM00789	Colorectal Carcinoma	GDSC	EDDSGVPTP	DEG_COP1_1	54:62	Mutation altering degron motif	0.6752
p.P62S	ACH-000997	Colon/Colorectal Cancer	CCLE	EDDSGVPTP	DEG_COP1_1	54:62	Mutation altering degron motif	0.6752
p.P62S	ACH-001061	Colon/Colorectal Cancer	CCLE	EDDSGVPTP	DEG_COP1_1	54:62	Mutation altering degron motif	0.6752
p.P62S	HCT-15	large intestine	COSMIC	EDDSGVPTP	DEG_COP1_1	54:62	Mutation altering degron motif	0.6752
p.D64Y	SIDM00168	Head and Neck Carcinoma	GDSC	EDDSGVPTP	DEG_COP1_1	54:62	Mutation rewiring degron network	0.2778
p.D64Y	SIDM00168	Head and Neck Carcinoma	GDSC	DSGVPT	DEG_SCF_TRCP1_1	56:61	Mutation rewiring degron network	0.25
p.D64Y	ACH-000549	Head and Neck Cancer	CCLE	EDDSGVPTP	DEG_COP1_1	54:62	Mutation rewiring degron network	0.2778
p.D64Y	ACH-000549	Head and Neck Cancer	CCLE	DSGVPT	DEG_SCF_TRCP1_1	56:61	Mutation rewiring degron network	0.25

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*NOTE: the Kaplan plots were collected from OncoLnc