p.N584S | TCGA-5P-A9JZ | KIRP | TCGA | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation altering degron motif | 0.7069 |
p.N584S | TCGA-B1-5398 | KIRP | TCGA | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation altering degron motif | 0.7069 |
p.N584S | DO18392 | KIRC | ICGC | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation altering degron motif | 0.7069 |
p.N584S | DO20930 | KIRP | ICGC | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation altering degron motif | 0.7069 |
p.N584S | DO223945 | KIRP | ICGC | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation altering degron motif | 0.7069 |
p.N584S | ACH-000016 | Kidney Cancer | CCLE | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation altering degron motif | 0.7069 |
p.N587T | TCGA-A6-5657 | COAD | TCGA | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.2778 |
p.N587T | DO10459 | COAD | ICGC | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.2778 |
p.K592T | TCGA-A8-A086 | BRCA | TCGA | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation substituting flanking lysine | 0.25 |
p.K592T | TCGA-W5-AA39 | CHOL | TCGA | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation substituting flanking lysine | 0.25 |
p.K592T | DO4671 | BRCA | ICGC | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation substituting flanking lysine | 0.25 |
p.K592T | DO231583 | LINC | ICGC | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation substituting flanking lysine | 0.25 |
p.K592T | DO45237 | LIRI | ICGC | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation substituting flanking lysine | 0.25 |
p.K196N | TCGA-AA-A010 | COAD | TCGA | SISTPPIVPDI | DEG_COP1_1 | 184:194 | Mutation blocking ubiquitination signal | 0.7222 |
p.K196N | TCGA-AP-A056 | UCEC | TCGA | SISTPPIVPDI | DEG_COP1_1 | 184:194 | Mutation blocking ubiquitination signal | 0.7222 |
p.K196N | DO222884 | COCA | ICGC | SISTPPIVPDI | DEG_COP1_1 | 184:194 | Mutation blocking ubiquitination signal | 0.7222 |
p.K196N | DO43971 | UCEC | ICGC | SISTPPIVPDI | DEG_COP1_1 | 184:194 | Mutation blocking ubiquitination signal | 0.7222 |
p.A594T | TCGA-AB-2806 | LAML | TCGA | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.0833 |
p.A594T | DO21283 | LAML | ICGC | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.0833 |
p.T156M | TCGA-AP-A051 | UCEC | TCGA | VNTSS | DEG_SPOP_SBC_1 | 154:158 | Mutation altering degron motif | 0.7423 |
p.T156M | DO232761 | PBCA | ICGC | VNTSS | DEG_SPOP_SBC_1 | 154:158 | Mutation altering degron motif | 0.7423 |
p.T156M | DO42673 | UCEC | ICGC | VNTSS | DEG_SPOP_SBC_1 | 154:158 | Mutation altering degron motif | 0.7423 |
p.Q202H | TCGA-AP-A1DP | UCEC | TCGA | SISTPPIVPDI | DEG_COP1_1 | 184:194 | Mutation rewiring degron network | 0.1111 |
p.Q202H | DO42336 | UCEC | ICGC | SISTPPIVPDI | DEG_COP1_1 | 184:194 | Mutation rewiring degron network | 0.1111 |
p.K595R | TCGA-BP-5184 | KIRC | TCGA | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation substituting flanking lysine | 0.1667 |
p.K595R | DO18859 | KIRC | ICGC | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation substituting flanking lysine | 0.1667 |
p.P188L | TCGA-BQ-7050 | KIRP | TCGA | SISTPPIVPDI | DEG_COP1_1 | 184:194 | Mutation altering degron motif | 0.6471 |
p.P188L | DO20877 | KIRP | ICGC | SISTPPIVPDI | DEG_COP1_1 | 184:194 | Mutation altering degron motif | 0.6471 |
p.P188L | SIDM01078 | Small Cell Lung Carcinoma | GDSC | SISTPPIVPDI | DEG_COP1_1 | 184:194 | Mutation altering degron motif | 0.6471 |
p.P188L | ACH-000790 | Lung Cancer | CCLE | SISTPPIVPDI | DEG_COP1_1 | 184:194 | Mutation altering degron motif | 0.6471 |
p.P188L | SHP-77 | lung | COSMIC | SISTPPIVPDI | DEG_COP1_1 | 184:194 | Mutation altering degron motif | 0.6471 |
p.S590R | TCGA-BQ-7058 | KIRP | TCGA | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.1944 |
p.S590R | TCGA-CD-A4MI | STAD | TCGA | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.1944 |
p.S590R | TCGA-W5-AA39 | CHOL | TCGA | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.1944 |
p.S590R | DO225046 | BRCA | ICGC | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.1944 |
p.S590R | DO20788 | KIRP | ICGC | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.1944 |
p.S590R | DO50949 | LICA | ICGC | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.1944 |
p.S590R | DO44790 | LICA | ICGC | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.1944 |
p.S590R | DO44802 | LICA | ICGC | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.1944 |
p.S590R | DO231690 | LINC | ICGC | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.1944 |
p.S590R | DO231672 | LINC | ICGC | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.1944 |
p.S590R | DO231887 | LINC | ICGC | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.1944 |
p.S590R | DO50808 | LIRI | ICGC | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.1944 |
p.S590R | DO45267 | LIRI | ICGC | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.1944 |
p.S590R | DO47717 | STAD | ICGC | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.1944 |
p.N571H | TCGA-CA-6717 | COAD | TCGA | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.0556 |
p.N571H | DO8264 | COAD | ICGC | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.0556 |
p.P192H | TCGA-CV-7100 | HNSC | TCGA | SISTPPIVPDI | DEG_COP1_1 | 184:194 | Mutation altering degron motif | 0.7694 |
p.P192H | DO15503 | HNSC | ICGC | SISTPPIVPDI | DEG_COP1_1 | 184:194 | Mutation altering degron motif | 0.7694 |
p.E580K | TCGA-DK-A1AC | BLCA | TCGA | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.3056 |
p.E580K | TCGA-XF-A9SJ | BLCA | TCGA | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.3056 |
p.E580K | TCGA-ZF-A9RC | BLCA | TCGA | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.3056 |
p.E580K | DO219045 | BLCA | ICGC | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.3056 |
p.E580K | DO219068 | BLCA | ICGC | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.3056 |
p.E580K | DO514 | BLCA | ICGC | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.3056 |
p.E586K | TCGA-DK-A1AC | BLCA | TCGA | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.3056 |
p.E586K | TCGA-EK-A2RJ | CESC | TCGA | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.3056 |
p.E586K | DO514 | BLCA | ICGC | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.3056 |
p.E586K | DO49950 | CESC | ICGC | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.3056 |
p.A594V | TCGA-DK-A1AE | BLCA | TCGA | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.0833 |
p.A594V | DO498 | BLCA | ICGC | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.0833 |
p.L198F | TCGA-DU-6407 | LGG | TCGA | SISTPPIVPDI | DEG_COP1_1 | 184:194 | Mutation rewiring degron network | 0.2222 |
p.L198F | DO22295 | LGG | ICGC | SISTPPIVPDI | DEG_COP1_1 | 184:194 | Mutation rewiring degron network | 0.2222 |
p.K592E | TCGA-DZ-6134 | KIRP | TCGA | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation substituting flanking lysine | 0.25 |
p.K592E | DO20944 | KIRP | ICGC | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation substituting flanking lysine | 0.25 |
p.K592N | TCGA-EB-A3XC | SKCM | TCGA | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation substituting flanking lysine | 0.25 |
p.K592N | DO225217 | BRCA | ICGC | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation substituting flanking lysine | 0.25 |
p.K592N | DO227566 | BRCA | ICGC | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation substituting flanking lysine | 0.25 |
p.K592N | DO37579 | SKCM | ICGC | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation substituting flanking lysine | 0.25 |
p.P163T | TCGA-EE-A29G | SKCM | TCGA | VNTSS | DEG_SPOP_SBC_1 | 154:158 | Mutation rewiring degron network | 0.1944 |
p.P163T | DO47303 | SKCM | ICGC | VNTSS | DEG_SPOP_SBC_1 | 154:158 | Mutation rewiring degron network | 0.1944 |
p.P581Q | TCGA-EE-A2GN | SKCM | TCGA | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation altering degron motif | 0.5924 |
p.P581Q | DO37896 | SKCM | ICGC | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation altering degron motif | 0.5924 |
p.S593T | TCGA-EJ-7331 | PRAD | TCGA | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.1111 |
p.S593T | DO36301 | PRAD | ICGC | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.1111 |
p.N584I | TCGA-EV-5903 | KIRP | TCGA | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation altering degron motif | 0.728 |
p.N584I | DO20890 | KIRP | ICGC | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation altering degron motif | 0.728 |
p.S591P | TCGA-G3-AAV0 | LIHC | TCGA | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.1667 |
p.S591P | DO52294 | LIHC | ICGC | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.1667 |
p.S591P | DO23184 | LINC | ICGC | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.1667 |
p.S591P | DO45293 | LIRI | ICGC | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.1667 |
p.S591P | DO45165 | LIRI | ICGC | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.1667 |
p.T575A | TCGA-G4-6628 | COAD | TCGA | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.1667 |
p.T575A | DO10132 | COAD | ICGC | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.1667 |
p.T575A | DO44790 | LICA | ICGC | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.1667 |
p.P163H | TCGA-GN-A262 | SKCM | TCGA | VNTSS | DEG_SPOP_SBC_1 | 154:158 | Mutation rewiring degron network | 0.1944 |
p.P163H | DO37515 | SKCM | ICGC | VNTSS | DEG_SPOP_SBC_1 | 154:158 | Mutation rewiring degron network | 0.1944 |
p.T579A | TCGA-IA-A83S | KIRP | TCGA | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.2778 |
p.T579A | DO51563 | KIRP | ICGC | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.2778 |
p.S590N | TCGA-PJ-A8JU | KIRP | TCGA | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.1944 |
p.S590N | DO48523 | KIRP | ICGC | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.1944 |
p.S590G | TCGA-SX-A71U | KIRP | TCGA | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.1944 |
p.S590G | DO49779 | KIRP | ICGC | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.1944 |
p.E586G | TCGA-W5-AA39 | CHOL | TCGA | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.3056 |
p.S577L | DO227790 | BRCA | ICGC | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.2222 |
p.V154A | DO230343 | COCA | ICGC | VNTSS | DEG_SPOP_SBC_1 | 154:158 | Mutation altering degron motif | 0.5825 |
p.E586D | DO234345 | ESAD | ICGC | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.3056 |
p.Q572H | DO229035 | LICA | ICGC | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.0833 |
p.V585G | DO50951 | LICA | ICGC | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation altering degron motif | 0.6421 |
p.E583A | DO23264 | LINC | ICGC | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation altering degron motif | 0.7701 |
p.Q589H | DO23232 | LINC | ICGC | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.2222 |
p.K576T | DO231799 | LINC | ICGC | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation substituting flanking lysine | 0.3056 |
p.A144V | DO231837 | LINC | ICGC | VNTSS | DEG_SPOP_SBC_1 | 154:158 | Mutation rewiring degron network | 0.0556 |
p.N162Y | DO228176 | PBCA | ICGC | VNTSS | DEG_SPOP_SBC_1 | 154:158 | Mutation rewiring degron network | 0.2222 |
p.T579S | DO231315 | THCA | ICGC | PKENV | DEG_APCC_KENBOX_2 | 581:585 | Mutation rewiring degron network | 0.2778 |
p.I190V | SIDM00694 | Other Solid Cancers | GDSC | SISTPPIVPDI | DEG_COP1_1 | 184:194 | Mutation altering degron motif | 0.5965 |
p.I190V | SIDM01664 | Prostate Carcinoma | GDSC | SISTPPIVPDI | DEG_COP1_1 | 184:194 | Mutation altering degron motif | 0.5965 |
p.P146R | SIDM00704 | Small Cell Lung Carcinoma | GDSC | VNTSS | DEG_SPOP_SBC_1 | 154:158 | Mutation rewiring degron network | 0.1111 |
p.P146R | ACH-000639 | Lung Cancer | CCLE | VNTSS | DEG_SPOP_SBC_1 | 154:158 | Mutation rewiring degron network | 0.1111 |
p.P146R | NCI-H211 | lung | COSMIC | VNTSS | DEG_SPOP_SBC_1 | 154:158 | Mutation rewiring degron network | 0.1111 |
p.Q195H | SIDM01588 | Endometrial Carcinoma | GDSC | SISTPPIVPDI | DEG_COP1_1 | 184:194 | Mutation rewiring degron network | 0.3056 |
p.Q195H | ACH-000993 | Endometrial/Uterine Cancer | CCLE | SISTPPIVPDI | DEG_COP1_1 | 184:194 | Mutation rewiring degron network | 0.3056 |