DegronMD - O95400(CD2BP2)

CD2BP2

Please click HERE for better display.

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S247P	TCGA-BR-6452	STAD	TCGA	PTPPPS	DEG_SCF_FBW7_1	242:247	Mutation altering degron motif	0.7863
p.S247P	DO38404	STAD	ICGC	PTPPPS	DEG_SCF_FBW7_1	242:247	Mutation altering degron motif	0.7863
p.P242L	TCGA-MP-A4TK	LUAD	TCGA	PTPPPS	DEG_SCF_FBW7_1	242:247	Mutation altering degron motif	0.6471
p.P242L	DO45384	LUAD	ICGC	PTPPPS	DEG_SCF_FBW7_1	242:247	Mutation altering degron motif	0.6471
p.A256V	DO233127	GACA	ICGC	PTPPPS	DEG_SCF_FBW7_1	242:247	Mutation rewiring degron network	0.0833
p.A256V	DO233127	GACA	ICGC	LDMFAE	LIG_APCC_ABBA_1	248:253	Mutation rewiring degron network	0.25
p.A256E	DO229035	LICA	ICGC	PTPPPS	DEG_SCF_FBW7_1	242:247	Mutation rewiring degron network	0.0833
p.A256E	DO229035	LICA	ICGC	LDMFAE	LIG_APCC_ABBA_1	248:253	Mutation rewiring degron network	0.25
p.P239L	DO232761	PBCA	ICGC	PTPPPS	DEG_SCF_FBW7_1	242:247	Mutation rewiring degron network	0.25
p.P239L	DO232761	PBCA	ICGC	LDMFAE	LIG_APCC_ABBA_1	248:253	Mutation rewiring degron network	0.0833
p.P246S	SIDM01387	Small Cell Lung Carcinoma	GDSC	PTPPPS	DEG_SCF_FBW7_1	242:247	Mutation altering degron motif	0.5641
p.P246S	ACH-000921	Lung Cancer	CCLE	PTPPPS	DEG_SCF_FBW7_1	242:247	Mutation altering degron motif	0.5641

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc