DegronMD - O95755(RAB36)

FUNCTION: Protein transport. Probably involved in vesicular traffic (By similarity). {ECO:0000250}.

GO - Biological processes (BP): protein transport [GO:0015031]

GO - Molecular function (MF): GTPase activity [GO:0003924]; GTP binding [GO:0005525]

GO - Cellular component (CC): Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.T23M	SIDM01088	Endometrial Carcinoma	GDSC	PPTTS	DEG_SPOP_SBC_1	21:25	Mutation altering degron motif	0.8534
p.T23M	ACH-000965	Endometrial/Uterine Cancer	CCLE	PPTTS	DEG_SPOP_SBC_1	21:25	Mutation altering degron motif	0.8534
p.T23M	RL95-2	endometrium	COSMIC	PPTTS	DEG_SPOP_SBC_1	21:25	Mutation altering degron motif	0.8534
p.T26M	TCGA-DU-6392	LGG	TCGA	PPTTS	DEG_SPOP_SBC_1	21:25	Mutation blocking phosphorylation signal	0.75
p.T26M	DO22237	LGG	ICGC	PPTTS	DEG_SPOP_SBC_1	21:25	Mutation blocking phosphorylation signal	0.75
p.T23M	SIDM01088	Endometrial Carcinoma	GDSC	PTQTPPTT	DEG_SCF_FBW7_1	17:24	Mutation altering degron motif	0.7423
p.T23M	ACH-000965	Endometrial/Uterine Cancer	CCLE	PTQTPPTT	DEG_SCF_FBW7_1	17:24	Mutation altering degron motif	0.7423
p.T23M	RL95-2	endometrium	COSMIC	PTQTPPTT	DEG_SCF_FBW7_1	17:24	Mutation altering degron motif	0.7423
p.T26M	TCGA-DU-6392	LGG	TCGA	PTQTPPTT	DEG_SCF_FBW7_1	17:24	Mutation blocking phosphorylation signal	0.7222
p.T26M	DO22237	LGG	ICGC	PTQTPPTT	DEG_SCF_FBW7_1	17:24	Mutation blocking phosphorylation signal	0.7222
p.S70P	ACH-000436	Myeloma	CCLE	MRSSLTPLG	DEG_APCC_DBOX_1	67:75	Mutation altering degron motif	0.6752
p.S69P	ACH-000948	Gastric Cancer	CCLE	MRSSLTPLG	DEG_APCC_DBOX_1	67:75	Mutation altering degron motif	0.6752
p.S69P	23132-87	stomach	COSMIC	MRSSLTPLG	DEG_APCC_DBOX_1	67:75	Mutation altering degron motif	0.6752
p.P22H	SIDM00120	Prostate Carcinoma	GDSC	PTQTPPTT	DEG_SCF_FBW7_1	17:24	Mutation altering degron motif	0.6583
p.P22H	SIDM00120	Prostate Carcinoma	GDSC	PPTTS	DEG_SPOP_SBC_1	21:25	Mutation altering degron motif	0.6583
p.P22H	ACH-000979	Prostate Cancer	CCLE	PTQTPPTT	DEG_SCF_FBW7_1	17:24	Mutation altering degron motif	0.6583
p.P22H	ACH-000979	Prostate Cancer	CCLE	PPTTS	DEG_SPOP_SBC_1	21:25	Mutation altering degron motif	0.6583
p.P22H	DU-145	prostate	COSMIC	PTQTPPTT	DEG_SCF_FBW7_1	17:24	Mutation altering degron motif	0.6583
p.P22H	DU-145	prostate	COSMIC	PPTTS	DEG_SPOP_SBC_1	21:25	Mutation altering degron motif	0.6583
p.G75R	SIDM00477	Esophageal Carcinoma	GDSC	MRSSLTPLG	DEG_APCC_DBOX_1	67:75	Mutation altering degron motif	0.6457

Showing 1 to 20 of 67 entries

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Kaplan plot for RAB36 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

RAB36

UniProt ID: O95755

Entrez ID: 9609

Protein name: Ras-related protein Rab-36

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for RAB36 in