DegronMD - P03971(AMH)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S226R	TCGA-3A-A9IS	PAAD	TCGA	LQPRGEDSR	SCF_FBXL2	216:224	Mutation rewiring degron network	0.2778
p.S226R	DO51682	PAAD	ICGC	LQPRGEDSR	SCF_FBXL2	216:224	Mutation rewiring degron network	0.2778
p.S210F	DO6144	BRCA	ICGC	LQPRGEDSR	SCF_FBXL2	216:224	Mutation rewiring degron network	0.1667
p.R229W	DO233760	GACA	ICGC	LQPRGEDSR	SCF_FBXL2	216:224	Mutation rewiring degron network	0.1944
p.Q217R	DO233941	GACA	ICGC	LQPRGEDSR	SCF_FBXL2	216:224	Mutation altering degron motif	0.7329
p.S226I	DO228952	LICA	ICGC	LQPRGEDSR	SCF_FBXL2	216:224	Mutation rewiring degron network	0.2778
p.E221K	DO37418	SKCM	ICGC	LQPRGEDSR	SCF_FBXL2	216:224	Mutation altering degron motif	0.591
p.R229Q	SIDM01313	Colorectal Carcinoma	GDSC	LQPRGEDSR	SCF_FBXL2	216:224	Mutation rewiring degron network	0.1944
p.R123Q	SIDM00353	Other Sarcomas	GDSC	VVLHLE	LIG_APCC_ABBA_1	131:136	Mutation rewiring degron network	0.1111
p.R123Q	SIDM00571	Pancreatic Carcinoma	GDSC	VVLHLE	LIG_APCC_ABBA_1	131:136	Mutation rewiring degron network	0.1111
p.R123Q	SIDM00587	Biliary Tract Carcinoma	GDSC	VVLHLE	LIG_APCC_ABBA_1	131:136	Mutation rewiring degron network	0.1111
p.R123Q	SIDM01449	Pancreatic Carcinoma	GDSC	VVLHLE	LIG_APCC_ABBA_1	131:136	Mutation rewiring degron network	0.1111
p.P142S	SIDM01259	B-Lymphoblastic Leukemia	GDSC	VVLHLE	LIG_APCC_ABBA_1	131:136	Mutation rewiring degron network	0.1667
p.P142S	ACH-001669	Leukemia	CCLE	VVLHLE	LIG_APCC_ABBA_1	131:136	Mutation rewiring degron network	0.1667
p.P142S	ACH-002238	Leukemia	CCLE	VVLHLE	LIG_APCC_ABBA_1	131:136	Mutation rewiring degron network	0.1667
p.A232S	ACH-000817	Myeloma	CCLE	LQPRGEDSR	SCF_FBXL2	216:224	Mutation rewiring degron network	0.1111

Kaplan plot for AMH in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

AMH

UniProt ID: P03971

Entrez ID: 268

Protein name: Muellerian-inhibiting factor (Anti-Muellerian hormone) (AMH) (Muellerian-inhibiting substance) (MIS)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for AMH in