DegronMD - P11171(EPB41)

EPB41

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E860K	TCGA-A5-A0G2	UCEC	TCGA	VVVHQE	LIG_APCC_ABBA_1	853:858	Mutation rewiring degron network	0.2778
p.E860K	TCGA-A5-A0G2	UCEC	TCGA	KVVVHQE	LIG_APCC_ABBAyCdc20_2	852:858	Mutation rewiring degron network	0.2778
p.Q857K	TCGA-D3-A2JC	SKCM	TCGA	VVVHQE	LIG_APCC_ABBA_1	853:858	Mutation altering degron motif	0.5833
p.Q857K	TCGA-D3-A2JC	SKCM	TCGA	KVVVHQE	LIG_APCC_ABBAyCdc20_2	852:858	Mutation altering degron motif	0.5833
p.D863G	SIDM01664	Prostate Carcinoma	GDSC	VVVHQE	LIG_APCC_ABBA_1	853:858	Mutation rewiring degron network	0.1944
p.D863G	SIDM01664	Prostate Carcinoma	GDSC	KVVVHQE	LIG_APCC_ABBAyCdc20_2	852:858	Mutation rewiring degron network	0.1944
p.D863G	ACH-000952	Prostate Cancer	CCLE	VVVHQE	LIG_APCC_ABBA_1	853:858	Mutation rewiring degron network	0.1944
p.D863G	ACH-000952	Prostate Cancer	CCLE	KVVVHQE	LIG_APCC_ABBAyCdc20_2	852:858	Mutation rewiring degron network	0.1944
p.K852N	SIDM01494	Glioblastoma	GDSC	KVVVHQE	LIG_APCC_ABBAyCdc20_2	852:858	Mutation altering degron motif	0.6918
p.K852N	ACH-000445	Brain Cancer	CCLE	KVVVHQE	LIG_APCC_ABBAyCdc20_2	852:858	Mutation altering degron motif	0.6918

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*NOTE: the Kaplan plots were collected from OncoLnc