DegronMD - P57737(CORO7)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.L493R	TCGA-BH-A0EE	BRCA	TCGA	LTTPGES	DEG_SCF_FBW7_1	495:501	Mutation rewiring degron network	0.2778
p.G503S	TCGA-CA-6717	COAD	TCGA	LTTPGES	DEG_SCF_FBW7_1	495:501	Mutation rewiring degron network	0.2778
p.G499C	TCGA-EE-A181	SKCM	TCGA	LTTPGES	DEG_SCF_FBW7_1	495:501	Mutation altering degron motif	0.6489
p.D78E	TCGA-QL-A97D	COAD	TCGA	FSPFDD	LIG_APCC_ABBA_1	85:90	Mutation rewiring degron network	0.1389
p.E492D	DO48409	BLCA	ICGC	LTTPGES	DEG_SCF_FBW7_1	495:501	Mutation rewiring degron network	0.25
p.E492D	DO229005	COCA	ICGC	LTTPGES	DEG_SCF_FBW7_1	495:501	Mutation rewiring degron network	0.25
p.V504L	DO51920	BLCA	ICGC	LTTPGES	DEG_SCF_FBW7_1	495:501	Mutation rewiring degron network	0.25
p.A498V	DO8722	COAD	ICGC	LTTPGES	DEG_SCF_FBW7_1	495:501	Mutation altering degron motif	0.6936
p.P87S	DO233903	GACA	ICGC	FSPFDD	LIG_APCC_ABBA_1	85:90	Mutation altering degron motif	0.6752
p.D99N	DO11854	GBM	ICGC	FSPFDD	LIG_APCC_ABBA_1	85:90	Mutation rewiring degron network	0.0833
p.S82C	DO228390	LICA	ICGC	FSPFDD	LIG_APCC_ABBA_1	85:90	Mutation rewiring degron network	0.25
p.T509M	DO38839	STAD	ICGC	LTTPGES	DEG_SCF_FBW7_1	495:501	Mutation rewiring degron network	0.1111
p.H76Y	ACH-000591	Brain Cancer	CCLE	FSPFDD	LIG_APCC_ABBA_1	85:90	Mutation rewiring degron network	0.0833
p.D90E	ACH-000879	Endometrial/Uterine Cancer	CCLE	FSPFDD	LIG_APCC_ABBA_1	85:90	Mutation altering degron motif	0.5647
p.A506V	ACH-000999	Colon/Colorectal Cancer	CCLE	LTTPGES	DEG_SCF_FBW7_1	495:501	Mutation rewiring degron network	0.1944
p.A506V	SNU-1040	large intestine	COSMIC	LTTPGES	DEG_SCF_FBW7_1	495:501	Mutation rewiring degron network	0.1944
p.V495M	A375	skin	COSMIC	LTTPGES	DEG_SCF_FBW7_1	495:501	Mutation altering degron motif	0.7208
p.K511N	MDA-MB-175-VII	breast	COSMIC	LTTPGES	DEG_SCF_FBW7_1	495:501	Mutation rewiring degron network	0.0556
p.A488V	SNU-1040	large intestine	COSMIC	LTTPGES	DEG_SCF_FBW7_1	495:501	Mutation rewiring degron network	0.1389

Kaplan plot for CORO7 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

CORO7

UniProt ID: P57737

Entrez ID: 79585

Protein name: Coronin-7 (Crn7) (70 kDa WD repeat tumor rejection antigen homolog)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for CORO7 in