DegronMD - Q13608(PEX6)

PEX6

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R575Q	TCGA-AJ-A3EK	UCEC	TCGA	VATTS	DEG_SPOP_SBC_1	570:574	Mutation rewiring degron network	0.3056
p.R575Q	DO41584	UCEC	ICGC	VATTS	DEG_SPOP_SBC_1	570:574	Mutation rewiring degron network	0.3056
p.Q584H	TCGA-C5-A7UC	CESC	TCGA	VATTS	DEG_SPOP_SBC_1	570:574	Mutation rewiring degron network	0.0556
p.Q584H	DO49889	CESC	ICGC	VATTS	DEG_SPOP_SBC_1	570:574	Mutation rewiring degron network	0.0556
p.Q146R	DO229257	THCA	ICGC	TRPALQGLL	DEG_APCC_DBOX_1	141:149	Mutation altering degron motif	0.6218
p.T573I	SIDM00669	Pancreatic Carcinoma	GDSC	VATTS	DEG_SPOP_SBC_1	570:574	Mutation altering degron motif	0.7078
p.T573I	SIDM00429	B-Lymphoblastic Leukemia	GDSC	VATTS	DEG_SPOP_SBC_1	570:574	Mutation altering degron motif	0.7078
p.T573I	SIDM00887	Other Solid Cancers	GDSC	VATTS	DEG_SPOP_SBC_1	570:574	Mutation altering degron motif	0.7078
p.R137Q	SIDM00784	Glioma	GDSC	TRPALQGLL	DEG_APCC_DBOX_1	141:149	Mutation rewiring degron network	0.2222
p.R137Q	ACH-000126	Brain Cancer	CCLE	TRPALQGLL	DEG_APCC_DBOX_1	141:149	Mutation rewiring degron network	0.2222
p.D582N	ACH-000923	Lymphoma	CCLE	VATTS	DEG_SPOP_SBC_1	570:574	Mutation rewiring degron network	0.1111
p.L155V	ACH-001441	Eye Cancer	CCLE	TRPALQGLL	DEG_APCC_DBOX_1	141:149	Mutation rewiring degron network	0.1667

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*NOTE: the Kaplan plots were collected from OncoLnc