DegronMD - Q14940(SLC9A5)

SLC9A5

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.W886L	TCGA-18-3414	LUSC	TCGA	IQFNRGSR	SCF_FBXL2	888:895	Mutation rewiring degron network	0.2778
p.W886L	DO26629	LUSC	ICGC	IQFNRGSR	SCF_FBXL2	888:895	Mutation rewiring degron network	0.2778
p.G880C	TCGA-A5-A1OF	UCEC	TCGA	IQFNRGSR	SCF_FBXL2	888:895	Mutation rewiring degron network	0.1111
p.G880C	DO42568	UCEC	ICGC	IQFNRGSR	SCF_FBXL2	888:895	Mutation rewiring degron network	0.1111
p.G544C	TCGA-AX-A06F	UCEC	TCGA	VLSST	DEG_SPOP_SBC_1	546:550	Mutation rewiring degron network	0.2778
p.G544C	DO41752	UCEC	ICGC	VLSST	DEG_SPOP_SBC_1	546:550	Mutation rewiring degron network	0.2778
p.V546I	TCGA-BG-A0MT	UCEC	TCGA	VLSST	DEG_SPOP_SBC_1	546:550	Mutation altering degron motif	0.7076
p.V546I	DO41698	UCEC	ICGC	VLSST	DEG_SPOP_SBC_1	546:550	Mutation altering degron motif	0.7076
p.V546I	SIDM01943	Colorectal Carcinoma	GDSC	VLSST	DEG_SPOP_SBC_1	546:550	Mutation altering degron motif	0.7076
p.L896M	TCGA-DU-6392	LGG	TCGA	IQFNRGSR	SCF_FBXL2	888:895	Mutation rewiring degron network	0.3056
p.L896M	DO22237	LGG	ICGC	IQFNRGSR	SCF_FBXL2	888:895	Mutation rewiring degron network	0.3056
p.S548F	TCGA-TN-A7HL	HNSC	TCGA	VLSST	DEG_SPOP_SBC_1	546:550	Mutation altering degron motif	0.7982
p.S548F	DO219080	HNSC	ICGC	VLSST	DEG_SPOP_SBC_1	546:550	Mutation altering degron motif	0.7982
p.A536T	DO233709	GACA	ICGC	VLSST	DEG_SPOP_SBC_1	546:550	Mutation rewiring degron network	0.0556
p.F539L	DO23336	LINC	ICGC	VLSST	DEG_SPOP_SBC_1	546:550	Mutation rewiring degron network	0.1389
p.S559G	DO220955	WT	ICGC	VLSST	DEG_SPOP_SBC_1	546:550	Mutation blocking phosphorylation signal	0.5278

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*NOTE: the Kaplan plots were collected from OncoLnc