DegronMD - Q5GJ75(TNFAIP8L3)

TNFAIP8L3

Please click HERE for better display.

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P107L	TCGA-BF-A5EQ	SKCM	TCGA	DSGEQS	DEG_SCF_TRCP1_1	92:97	Mutation rewiring degron network	0.0556
p.P107L	DO219452	SKCM	ICGC	DSGEQS	DEG_SCF_TRCP1_1	92:97	Mutation rewiring degron network	0.0556
p.D92N	DO232051	ORCA	ICGC	DSDSGE	DEG_Kelch_Keap1_1	90:95	Mutation altering degron motif	0.6932
p.D92N	DO232051	ORCA	ICGC	DSGEQS	DEG_SCF_TRCP1_1	92:97	Mutation altering degron motif	0.6932
p.T103S	SIDM00855	Other Sarcomas	GDSC	DSDSGE	DEG_Kelch_Keap1_1	90:95	Mutation blocking phosphorylation signal	0.5556
p.T103S	SIDM00855	Other Sarcomas	GDSC	DSGEQS	DEG_SCF_TRCP1_1	92:97	Mutation blocking phosphorylation signal	0.6111

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc