DegronMD - Q5JPF3(ANKRD36C)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Data table is loading....

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.M974L	SIDM00216	Colorectal Carcinoma	GDSC	DKENS	DEG_APCC_KENBOX_2	966:970	Mutation rewiring degron network	0.2222
p.M974L	ACH-000989	Colon/Colorectal Cancer	CCLE	DKENS	DEG_APCC_KENBOX_2	966:970	Mutation rewiring degron network	0.2222
p.M974L	SNU-175	large intestine	COSMIC	DKENS	DEG_APCC_KENBOX_2	966:970	Mutation rewiring degron network	0.2222
p.H956Q	SIDM00680	Colorectal Carcinoma	GDSC	DKENS	DEG_APCC_KENBOX_2	966:970	Mutation rewiring degron network	0.0556
p.H956Q	ACH-000957	Colon/Colorectal Cancer	CCLE	DKENS	DEG_APCC_KENBOX_2	966:970	Mutation rewiring degron network	0.0556
p.H956Q	LS-180	large intestine	COSMIC	DKENS	DEG_APCC_KENBOX_2	966:970	Mutation rewiring degron network	0.0556
p.T964A	SIDM00744	Non-Small Cell Lung Carcinoma	GDSC	DKENS	DEG_APCC_KENBOX_2	966:970	Mutation blocking phosphorylation signal	0.7222
p.T964A	ACH-000893	Lung Cancer	CCLE	DKENS	DEG_APCC_KENBOX_2	966:970	Mutation blocking phosphorylation signal	0.7222
p.T964A	NCI-H1651	lung	COSMIC	DKENS	DEG_APCC_KENBOX_2	966:970	Mutation blocking phosphorylation signal	0.7222
p.N969D	SIDM00875	Breast Carcinoma	GDSC	DKENS	DEG_APCC_KENBOX_2	966:970	Mutation altering degron motif	0.6932
p.A975P	SIDM01372	Pancreatic Carcinoma	GDSC	DKENS	DEG_APCC_KENBOX_2	966:970	Mutation rewiring degron network	0.1944
p.A975P	ACH-000266	Pancreatic Cancer	CCLE	DKENS	DEG_APCC_KENBOX_2	966:970	Mutation rewiring degron network	0.1944
p.Q958K	ACH-001857	Bile Duct Cancer	CCLE	DKENS	DEG_APCC_KENBOX_2	966:970	Mutation rewiring degron network	0.1111
p.Q1158K	ACH-002664	Colon/Colorectal Cancer	CCLE	VQTST	DEG_SPOP_SBC_1	1151:1155	Mutation rewiring degron network	0.25

Kaplan plot for ANKRD36C in

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

ANKRD36C

UniProt ID: Q5JPF3

Entrez ID:

Protein name: Ankyrin repeat domain-containing protein 36C (Protein immuno-reactive with anti-PTH polyclonal antibodies)

External links: UniprotKB HGNC RefSeq COSMIC

Data table is loading....

Kaplan plot for ANKRD36C in