DegronMD

Uniprot ID: Q5JPF3

Source protein: Ankyrin repeat domain-containing protein 36C

Source gene: ANKRD36C

Class: DEG_SPOP_SBC_1

Location: 1151:1155

E3 ligase: SPOP

DEGRON score: 0.8174

ASA_SCORE: 87.64

COIL: 0.8302

CONS_SCORE: 0.3718

DSS_SCORE: 0.6343

HELIX: 0.1334

FCONS_SCORE: 0.8877

RIG_SCORE: 0.6975

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.Q1158K	ACH-002664	Colon/Colorectal Cancer	CCLE	VQTST	DEG_SPOP_SBC_1	0.25

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q8N2N9	Ankyrin repeat domain-containing protein 36B	DEG_SPOP_SBC_1	725:729	VQTST	SPOP	0.996	More...
A6QL64	Ankyrin repeat domain-containing protein 36A	DEG_SPOP_SBC_1	1287:1291	VQTST	SPOP	0.7936	More...
Q5JPF3	Ankyrin repeat domain-containing protein 36C	DEG_SPOP_SBC_1	1151:1155	VQTST	SPOP	0.8174	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons