DegronMD - Q5KSL6(DGKK)

DGKK

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A1258T	SIDM02059	Colorectal Carcinoma	GDSC	PLTPSRS	DEG_SCF_FBW7_1	1263:1269	Mutation rewiring degron network	0.1944
p.S1269Y	SIDM02027	Colorectal Carcinoma	GDSC	PLTPSRS	DEG_SCF_FBW7_1	1263:1269	Mutation altering degron motif	0.712
p.Q1017K	SIDM00403	T-Lymphoblastic Leukemia	GDSC	QRPGLIKIR	DEG_APCC_DBOX_1	1017:1025	Mutation altering degron motif	0.5833
p.Q1017E	SIDM00399	Head and Neck Carcinoma	GDSC	QRPGLIKIR	DEG_APCC_DBOX_1	1017:1025	Mutation altering degron motif	0.5633
p.D1261G	SIDM01259	B-Lymphoblastic Leukemia	GDSC	PLTPSRS	DEG_SCF_FBW7_1	1263:1269	Mutation rewiring degron network	0.2778
p.R1254C	SIDM01611	Endometrial Carcinoma	GDSC	PLTPSRS	DEG_SCF_FBW7_1	1263:1269	Mutation rewiring degron network	0.0833
p.R1254H	SIDM01619	Endometrial Carcinoma	GDSC	PLTPSRS	DEG_SCF_FBW7_1	1263:1269	Mutation rewiring degron network	0.0833

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*NOTE: the Kaplan plots were collected from OncoLnc