DegronMD - Q5TI25(NBPF14)

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.L434V	DO225335	BRCA	ICGC	SRELLEVVE	DEG_APCC_DBOX_1	430:438	Mutation altering degron motif	0.6765
p.L434V	DO229181	THCA	ICGC	SRELLEVVE	DEG_APCC_DBOX_1	430:438	Mutation altering degron motif	0.6765
p.L434V	DO229253	THCA	ICGC	SRELLEVVE	DEG_APCC_DBOX_1	430:438	Mutation altering degron motif	0.6765
p.V755A	DO225376	BRCA	ICGC	SRELLEVVE	DEG_APCC_DBOX_1	749:757	Mutation altering degron motif	0.5825
p.V755A	DO229275	THCA	ICGC	SRELLEVVE	DEG_APCC_DBOX_1	749:757	Mutation altering degron motif	0.5825
p.V755A	DO229224	THCA	ICGC	SRELLEVVE	DEG_APCC_DBOX_1	749:757	Mutation altering degron motif	0.5825
p.G423D	DO227486	LAML	ICGC	SRELLEVVE	DEG_APCC_DBOX_1	430:438	Mutation rewiring degron network	0.1389
p.G423D	DO224576	LUSC	ICGC	SRELLEVVE	DEG_APCC_DBOX_1	430:438	Mutation rewiring degron network	0.1389
p.G423D	DO224589	LUSC	ICGC	SRELLEVVE	DEG_APCC_DBOX_1	430:438	Mutation rewiring degron network	0.1389
p.G423D	DO224610	LUSC	ICGC	SRELLEVVE	DEG_APCC_DBOX_1	430:438	Mutation rewiring degron network	0.1389
p.G423D	DO229121	THCA	ICGC	SRELLEVVE	DEG_APCC_DBOX_1	430:438	Mutation rewiring degron network	0.1389
p.G423D	DO229253	THCA	ICGC	SRELLEVVE	DEG_APCC_DBOX_1	430:438	Mutation rewiring degron network	0.1389
p.G423D	DO229227	THCA	ICGC	SRELLEVVE	DEG_APCC_DBOX_1	430:438	Mutation rewiring degron network	0.1389
p.G423D	DO229250	THCA	ICGC	SRELLEVVE	DEG_APCC_DBOX_1	430:438	Mutation rewiring degron network	0.1389
p.V436A	DO229167	THCA	ICGC	SRELLEVVE	DEG_APCC_DBOX_1	430:438	Mutation altering degron motif	0.5825
p.L753V	DO229253	THCA	ICGC	SRELLEVVE	DEG_APCC_DBOX_1	749:757	Mutation altering degron motif	0.6765
p.G742D	DO229201	THCA	ICGC	SRELLEVVE	DEG_APCC_DBOX_1	749:757	Mutation rewiring degron network	0.1389
p.V756A	ACH-000407	Endometrial/Uterine Cancer	CCLE	SRELLEVVE	DEG_APCC_DBOX_1	749:757	Mutation altering degron motif	0.6936
p.V756A	ACH-000513	Kidney Cancer	CCLE	SRELLEVVE	DEG_APCC_DBOX_1	749:757	Mutation altering degron motif	0.6936
p.V756A	ACH-001210	Rhabdoid	CCLE	SRELLEVVE	DEG_APCC_DBOX_1	749:757	Mutation altering degron motif	0.6936
p.Q443H	ACH-000869	Lung Cancer	CCLE	SRELLEVVE	DEG_APCC_DBOX_1	430:438	Mutation rewiring degron network	0.1944

DegronMD: protein-targeted degradation, mutation and drug response to degrons

NBPF14

UniProt ID: Q5TI25

Entrez ID:

Protein name: Neuroblastoma breakpoint family member 14

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for NBPF14 in