DegronMD - Q5U5Q3(MEX3C)

MEX3C

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.N44D	DO233888	GACA	ICGC	LRERLAALG	DEG_APCC_DBOX_1	48:56	Mutation rewiring degron network	0.2222
p.K41N	DO50006	HNSC	ICGC	LRERLAALG	DEG_APCC_DBOX_1	48:56	Mutation rewiring degron network	0.1389
p.R63L	DO228827	LICA	ICGC	LRERLAALG	DEG_APCC_DBOX_1	48:56	Mutation rewiring degron network	0.1389
p.K41E	DO229213	THCA	ICGC	LRERLAALG	DEG_APCC_DBOX_1	48:56	Mutation rewiring degron network	0.1389
p.P546L	SIDM00845	Burkitt's Lymphoma	GDSC	PSTPRLS	DEG_SCF_FBW7_1	539:545	Mutation rewiring degron network	0.3056
p.R534C	SIDM00518	Mesothelioma	GDSC	PSTPRLS	DEG_SCF_FBW7_1	539:545	Mutation rewiring degron network	0.1944
p.R534C	H290	pleura	COSMIC	PSTPRLS	DEG_SCF_FBW7_1	539:545	Mutation rewiring degron network	0.1944
p.I552V	SIDM00282	Colorectal Carcinoma	GDSC	PSTPRLS	DEG_SCF_FBW7_1	539:545	Mutation rewiring degron network	0.1389
p.I552V	CW-2	large intestine	COSMIC	PSTPRLS	DEG_SCF_FBW7_1	539:545	Mutation rewiring degron network	0.1389
p.R543H	SIDM01460	Glioma	GDSC	PSTPRLS	DEG_SCF_FBW7_1	539:545	Mutation altering degron motif	0.7133
p.H56Q	ACH-000549	Head and Neck Cancer	CCLE	LRERLAALG	DEG_APCC_DBOX_1	48:56	Mutation altering degron motif	0.7582

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*NOTE: the Kaplan plots were collected from OncoLnc