DegronMD - Q6NZY4(ZCCHC8)

ZCCHC8

Please click HERE for better display.

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E580K	TCGA-E7-A7XN	BLCA	TCGA	TLDEPEVPEI	DEG_COP1_1	577:586	Mutation altering degron motif	0.591
p.I586M	TCGA-F5-6814	READ	TCGA	TLDEPEVPEI	DEG_COP1_1	577:586	Mutation altering degron motif	0.6507
p.P494L	TCGA-IB-7651	PAAD	TCGA	PKGTPPLT	DEG_SCF_FBW7_1	489:496	Mutation altering degron motif	0.6471
p.T577M	TCGA-KN-8435	KICH	TCGA	TLDEPEVPEI	DEG_COP1_1	577:586	Mutation altering degron motif	0.8534
p.T577M	NCI-H2172	lung	COSMIC	TLDEPEVPEI	DEG_COP1_1	577:586	Mutation altering degron motif	0.8534
p.T505K	TCGA-PL-A8LZ	BRCA	TCGA	PKGTPPLT	DEG_SCF_FBW7_1	489:496	Mutation rewiring degron network	0.0833
p.P568R	Jurkat	haematopoietic and lymphoid tissue	COSMIC	TLDEPEVPEI	DEG_COP1_1	577:586	Mutation rewiring degron network	0.0833
p.V483I	NCI-H1155	lung	COSMIC	PKGTPPLT	DEG_SCF_FBW7_1	489:496	Mutation rewiring degron network	0.1667
p.P584S	JHH-1	liver	COSMIC	TLDEPEVPEI	DEG_COP1_1	577:586	Mutation altering degron motif	0.6752
p.E582D	SNU-C2B	large intestine	COSMIC	TLDEPEVPEI	DEG_COP1_1	577:586	Mutation altering degron motif	0.5647

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc