DegronMD - Q6ZVD7(STOX1)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R796I	TCGA-AA-3984	COAD	TCGA	LHATPGES	DEG_SCF_FBW7_1	805:812	Mutation rewiring degron network	0.0833
p.R796I	TCGA-AP-A056	UCEC	TCGA	LHATPGES	DEG_SCF_FBW7_1	805:812	Mutation rewiring degron network	0.0833
p.R796I	TCGA-AX-A05Z	UCEC	TCGA	LHATPGES	DEG_SCF_FBW7_1	805:812	Mutation rewiring degron network	0.0833
p.R796I	TCGA-EI-6917	READ	TCGA	LHATPGES	DEG_SCF_FBW7_1	805:812	Mutation rewiring degron network	0.0833
p.R796I	DO222830	BTCA	ICGC	LHATPGES	DEG_SCF_FBW7_1	805:812	Mutation rewiring degron network	0.0833
p.R796I	DO9002	COAD	ICGC	LHATPGES	DEG_SCF_FBW7_1	805:812	Mutation rewiring degron network	0.0833
p.R796I	DO36881	READ	ICGC	LHATPGES	DEG_SCF_FBW7_1	805:812	Mutation rewiring degron network	0.0833
p.R796I	DO40884	UCEC	ICGC	LHATPGES	DEG_SCF_FBW7_1	805:812	Mutation rewiring degron network	0.0833
p.R796I	DO43971	UCEC	ICGC	LHATPGES	DEG_SCF_FBW7_1	805:812	Mutation rewiring degron network	0.0833
p.C799Y	TCGA-AP-A1DK	UCEC	TCGA	LHATPGES	DEG_SCF_FBW7_1	805:812	Mutation rewiring degron network	0.1667
p.R941Q	TCGA-B5-A11E	UCEC	TCGA	DSGIDS	DEG_SCF_TRCP1_1	934:939	Mutation rewiring degron network	0.2778
p.E820K	TCGA-CN-4723	HNSC	TCGA	LHATPGES	DEG_SCF_FBW7_1	805:812	Mutation rewiring degron network	0.1111
p.E820K	DO14830	HNSC	ICGC	LHATPGES	DEG_SCF_FBW7_1	805:812	Mutation rewiring degron network	0.1111
p.D938Y	TCGA-DU-6392	LGG	TCGA	DSGIDS	DEG_SCF_TRCP1_1	934:939	Mutation altering degron motif	0.6214
p.E927Q	TCGA-E2-A10C	BRCA	TCGA	DSGIDS	DEG_SCF_TRCP1_1	934:939	Mutation rewiring degron network	0.1389
p.E927Q	DO1334	BRCA	ICGC	DSGIDS	DEG_SCF_TRCP1_1	934:939	Mutation rewiring degron network	0.1389
p.G946R	TCGA-EI-6507	READ	TCGA	DSGIDS	DEG_SCF_TRCP1_1	934:939	Mutation rewiring degron network	0.1389
p.P940T	TCGA-FS-A1ZQ	SKCM	TCGA	DSGIDS	DEG_SCF_TRCP1_1	934:939	Mutation rewiring degron network	0.3056
p.P940T	DO37442	SKCM	ICGC	DSGIDS	DEG_SCF_TRCP1_1	934:939	Mutation rewiring degron network	0.3056
p.R796T	TCGA-K4-A83P	BLCA	TCGA	LHATPGES	DEG_SCF_FBW7_1	805:812	Mutation rewiring degron network	0.0833
p.R796T	DO49787	BLCA	ICGC	LHATPGES	DEG_SCF_FBW7_1	805:812	Mutation rewiring degron network	0.0833
p.R796G	TCGA-VP-A87E	PRAD	TCGA	LHATPGES	DEG_SCF_FBW7_1	805:812	Mutation rewiring degron network	0.0833
p.R796G	DO51387	PRAD	ICGC	LHATPGES	DEG_SCF_FBW7_1	805:812	Mutation rewiring degron network	0.0833
p.P815S	DO233652	GACA	ICGC	LHATPGES	DEG_SCF_FBW7_1	805:812	Mutation rewiring degron network	0.25
p.P815S	DO50681	ORCA	ICGC	LHATPGES	DEG_SCF_FBW7_1	805:812	Mutation rewiring degron network	0.25
p.L817I	DO221117	MALY	ICGC	LHATPGES	DEG_SCF_FBW7_1	805:812	Mutation rewiring degron network	0.1944
p.L817I	ACH-001377	Pancreatic Cancer	CCLE	LHATPGES	DEG_SCF_FBW7_1	805:812	Mutation rewiring degron network	0.1944
p.P800Q	DO28923	OV	ICGC	LHATPGES	DEG_SCF_FBW7_1	805:812	Mutation rewiring degron network	0.1944
p.L813F	DO37961	SKCM	ICGC	LHATPGES	DEG_SCF_FBW7_1	805:812	Mutation rewiring degron network	0.3056
p.G935V	NCI-H2029	lung	COSMIC	DSGIDS	DEG_SCF_TRCP1_1	934:939	Mutation altering degron motif	0.7532
p.S819N	CAL-54	kidney	COSMIC	LHATPGES	DEG_SCF_FBW7_1	805:812	Mutation rewiring degron network	0.1389
p.Q795R	NCI-H1573	lung	COSMIC	LHATPGES	DEG_SCF_FBW7_1	805:812	Mutation substituting flanking lysine	0.1667

Kaplan plot for STOX1 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

STOX1

UniProt ID: Q6ZVD7

Entrez ID: 219736

Protein name: Storkhead-box protein 1 (Winged-helix domain-containing protein)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for STOX1 in