DegronMD - Q7Z4V5(HDGFL2)

HDGFL2

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P394L	SIDM00007	Other Solid Cancers	GDSC	PPSSS	DEG_SPOP_SBC_1	393:397	Mutation altering degron motif	0.6471
p.R216Q	SIDM00596	Endometrial Carcinoma	GDSC	DQDFTPEK	DEG_SCF_SKP2-CKS1_1	201:208	Mutation rewiring degron network	0.1111
p.R216Q	HEC-1	endometrium	COSMIC	DQDFTPEK	DEG_SCF_SKP2-CKS1_1	201:208	Mutation rewiring degron network	0.1111
p.P215S	SIDM00420	Bladder Carcinoma	GDSC	DQDFTPEK	DEG_SCF_SKP2-CKS1_1	201:208	Mutation rewiring degron network	0.1389
p.W82C	SIDM00217	Colorectal Carcinoma	GDSC	NNPHASYSAPP	CBL_PTK	86:96	Mutation rewiring degron network	0.2222
p.W82C	SNU-1040	large intestine	COSMIC	NNPHASYSAPP	CBL_PTK	86:96	Mutation rewiring degron network	0.2222
p.A90T	SIDM00217	Colorectal Carcinoma	GDSC	NNPHASYSAPP	CBL_PTK	86:96	Mutation altering degron motif	0.6028
p.A90T	SNU-1040	large intestine	COSMIC	NNPHASYSAPP	CBL_PTK	86:96	Mutation altering degron motif	0.6028
p.R290W	SIDM01609	Endometrial Carcinoma	GDSC	PPSSS	DEG_SPOP_SBC_1	297:301	Mutation rewiring degron network	0.1389

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*NOTE: the Kaplan plots were collected from OncoLnc