DegronMD - Q86UX6(STK32C)

STK32C

UniProt ID: Q86UX6

Entrez ID: 282974

Protein name: Serine/threonine-protein kinase 32C (EC 2.7.11.1) (PKE) (Yet another novel kinase 3)

External links: UniprotKB HGNC RefSeq COSMIC

Please click HERE for better display.

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Data table is loading....

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.Q94L	TCGA-38-4626	LUAD	TCGA	RRPVFDD	LIG_APCC_ABBAyCdc20_2	78:84	Mutation rewiring degron network	0.0556
p.D91Y	TCGA-55-1592	LUAD	TCGA	RRPVFDD	LIG_APCC_ABBAyCdc20_2	78:84	Mutation rewiring degron network	0.1389
p.D91N	TCGA-A5-A2K5	UCEC	TCGA	RRPVFDD	LIG_APCC_ABBAyCdc20_2	78:84	Mutation rewiring degron network	0.1389
p.M388L	TCGA-HD-7832	HNSC	TCGA	KGRLHCD	LIG_APCC_ABBAyCdc20_2	374:380	Mutation rewiring degron network	0.1111
p.A72V	DO220828	BRCA	ICGC	RRPVFDD	LIG_APCC_ABBAyCdc20_2	78:84	Mutation rewiring degron network	0.1667
p.G92D	DO3686	BRCA	ICGC	RRPVFDD	LIG_APCC_ABBAyCdc20_2	78:84	Mutation rewiring degron network	0.1111
p.E73K	DO51624	CESC	ICGC	RRPVFDD	LIG_APCC_ABBAyCdc20_2	78:84	Mutation rewiring degron network	0.1944
p.G369S	DO10116	COAD	ICGC	KGRLHCD	LIG_APCC_ABBAyCdc20_2	374:380	Mutation rewiring degron network	0.1944
p.V69M	DO222765	COCA	ICGC	RRPVFDD	LIG_APCC_ABBAyCdc20_2	78:84	Mutation rewiring degron network	0.0833
p.A68D	DO229008	LICA	ICGC	RRPVFDD	LIG_APCC_ABBAyCdc20_2	78:84	Mutation rewiring degron network	0.0556
p.A86T	DO50970	LICA	ICGC	RRPVFDD	LIG_APCC_ABBAyCdc20_2	78:84	Mutation rewiring degron network	0.2778
p.E73D	DO45183	LIRI	ICGC	RRPVFDD	LIG_APCC_ABBAyCdc20_2	78:84	Mutation rewiring degron network	0.1944
p.E73D	DO41572	UCEC	ICGC	RRPVFDD	LIG_APCC_ABBAyCdc20_2	78:84	Mutation rewiring degron network	0.1944
p.D88Y	DO23629	LUAD	ICGC	RRPVFDD	LIG_APCC_ABBAyCdc20_2	78:84	Mutation rewiring degron network	0.2222
p.G92E	DO49083	LUSC	ICGC	RRPVFDD	LIG_APCC_ABBAyCdc20_2	78:84	Mutation rewiring degron network	0.1111
p.N68D	DO36369	PRAD	ICGC	RRPVFDD	LIG_APCC_ABBAyCdc20_2	78:84	Mutation rewiring degron network	0.0556
p.G367W	DO37738	SKCM	ICGC	KGRLHCD	LIG_APCC_ABBAyCdc20_2	374:380	Mutation rewiring degron network	0.1389
p.A366V	DO47700	SKCM	ICGC	KGRLHCD	LIG_APCC_ABBAyCdc20_2	374:380	Mutation rewiring degron network	0.1111
p.L90M	DO47623	SKCM	ICGC	RRPVFDD	LIG_APCC_ABBAyCdc20_2	78:84	Mutation rewiring degron network	0.1667
p.R91C	DO223286	UCEC	ICGC	RRPVFDD	LIG_APCC_ABBAyCdc20_2	78:84	Mutation rewiring degron network	0.1389
p.R91C	DO42633	UCEC	ICGC	RRPVFDD	LIG_APCC_ABBAyCdc20_2	78:84	Mutation rewiring degron network	0.1389
p.R91C	ACH-000994	Endometrial/Uterine Cancer	CCLE	RRPVFDD	LIG_APCC_ABBAyCdc20_2	78:84	Mutation rewiring degron network	0.1389
p.G70R	DO42977	UCEC	ICGC	RRPVFDD	LIG_APCC_ABBAyCdc20_2	78:84	Mutation blocking phosphorylation signal	0.5556
p.K85R	SIDM00953	Small Cell Lung Carcinoma	GDSC	RRPVFDD	LIG_APCC_ABBAyCdc20_2	78:84	Mutation rewiring degron network	0.3056
p.K85R	CPC-N	lung	COSMIC	RRPVFDD	LIG_APCC_ABBAyCdc20_2	78:84	Mutation rewiring degron network	0.3056
p.T76N	SIDM00632	Non-Cancerous	GDSC	RRPVFDD	LIG_APCC_ABBAyCdc20_2	78:84	Mutation rewiring degron network	0.2778
p.T76N	IM-9	haematopoietic and lymphoid tissue	COSMIC	RRPVFDD	LIG_APCC_ABBAyCdc20_2	78:84	Mutation rewiring degron network	0.2778
p.L85V	ACH-000994	Endometrial/Uterine Cancer	CCLE	RRPVFDD	LIG_APCC_ABBAyCdc20_2	78:84	Mutation rewiring degron network	0.3056

Kaplan plot for STK32C in

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc