DegronMD - Q86XQ3(CATSPER3)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.V18A	TCGA-05-4396	LUAD	TCGA	VDTTS	DEG_SPOP_SBC_1	18:22	Mutation altering degron motif	0.5825
p.V18A	TCGA-BR-6452	STAD	TCGA	VDTTS	DEG_SPOP_SBC_1	18:22	Mutation altering degron motif	0.5825
p.V18A	DO23838	LUAD	ICGC	VDTTS	DEG_SPOP_SBC_1	18:22	Mutation altering degron motif	0.5825
p.V18A	DO38404	STAD	ICGC	VDTTS	DEG_SPOP_SBC_1	18:22	Mutation altering degron motif	0.5825
p.S22L	TCGA-A5-A0G1	UCEC	TCGA	VDTTS	DEG_SPOP_SBC_1	18:22	Mutation altering degron motif	0.7667
p.S22L	DO42472	UCEC	ICGC	VDTTS	DEG_SPOP_SBC_1	18:22	Mutation altering degron motif	0.7667
p.S22L	SIDM01205	Acute Myeloid Leukemia	GDSC	VDTTS	DEG_SPOP_SBC_1	18:22	Mutation altering degron motif	0.7667
p.S22L	SIDM01195	Acute Myeloid Leukemia	GDSC	VDTTS	DEG_SPOP_SBC_1	18:22	Mutation altering degron motif	0.7667
p.K30N	TCGA-AN-A046	BRCA	TCGA	VDTTS	DEG_SPOP_SBC_1	18:22	Mutation substituting flanking lysine	0.2222
p.K30N	DO1285	BRCA	ICGC	VDTTS	DEG_SPOP_SBC_1	18:22	Mutation substituting flanking lysine	0.2222
p.R11I	TCGA-EO-A22R	UCEC	TCGA	VISSS	DEG_SPOP_SBC_1	12:16	Mutation rewiring degron network	0.3056
p.R11I	TCGA-EO-A22R	UCEC	TCGA	VDTTS	DEG_SPOP_SBC_1	18:22	Mutation rewiring degron network	0.1389
p.R11I	DO42713	UCEC	ICGC	VISSS	DEG_SPOP_SBC_1	12:16	Mutation rewiring degron network	0.3056
p.R11I	DO42713	UCEC	ICGC	VDTTS	DEG_SPOP_SBC_1	18:22	Mutation rewiring degron network	0.1389
p.R8H	TCGA-EO-A3AY	UCEC	TCGA	VISSS	DEG_SPOP_SBC_1	12:16	Mutation rewiring degron network	0.2222
p.R8H	TCGA-EO-A3AY	UCEC	TCGA	VDTTS	DEG_SPOP_SBC_1	18:22	Mutation rewiring degron network	0.0556
p.R8H	DO43202	UCEC	ICGC	VISSS	DEG_SPOP_SBC_1	12:16	Mutation rewiring degron network	0.2222
p.R8H	DO43202	UCEC	ICGC	VDTTS	DEG_SPOP_SBC_1	18:22	Mutation rewiring degron network	0.0556
p.S16T	DO233550	PRAD	ICGC	VISSS	DEG_SPOP_SBC_1	12:16	Mutation altering degron motif	0.6005

Kaplan plot for CATSPER3 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

CATSPER3

UniProt ID: Q86XQ3

Entrez ID: 347732

Protein name: Cation channel sperm-associated protein 3 (CatSper3) (Ca(v)-like protein) (One-repeat calcium channel-like protein)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for CATSPER3 in