p.R183C | TCGA-06-5416 | GBM | TCGA | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation altering degron motif | 0.719 |
p.R183C | TCGA-19-5956 | GBM | TCGA | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation altering degron motif | 0.719 |
p.R183C | TCGA-AA-3510 | COAD | TCGA | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation altering degron motif | 0.719 |
p.R183C | TCGA-AZ-4315 | COAD | TCGA | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation altering degron motif | 0.719 |
p.R183C | TCGA-D8-A1Y1 | BRCA | TCGA | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation altering degron motif | 0.719 |
p.R183C | TCGA-EY-A1G8 | UCEC | TCGA | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation altering degron motif | 0.719 |
p.R183C | TCGA-J2-A4AD | LUAD | TCGA | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation altering degron motif | 0.719 |
p.R183C | DO1398 | BRCA | ICGC | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation altering degron motif | 0.719 |
p.R183C | DO7783 | COAD | ICGC | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation altering degron motif | 0.719 |
p.R183C | DO8842 | COAD | ICGC | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation altering degron motif | 0.719 |
p.R183C | DO13863 | GBM | ICGC | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation altering degron motif | 0.719 |
p.R183C | DO10880 | GBM | ICGC | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation altering degron motif | 0.719 |
p.R183C | DO23915 | LUAD | ICGC | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation altering degron motif | 0.719 |
p.R183C | DO43578 | UCEC | ICGC | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation altering degron motif | 0.719 |
p.R183C | ACH-000398 | Lymphoma | CCLE | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation altering degron motif | 0.719 |
p.R181Q | TCGA-A5-A2K5 | UCEC | TCGA | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation rewiring degron network | 0.3056 |
p.R181Q | TCGA-AA-3510 | COAD | TCGA | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation rewiring degron network | 0.3056 |
p.R181Q | TCGA-AA-3977 | COAD | TCGA | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation rewiring degron network | 0.3056 |
p.R181Q | TCGA-AG-A002 | READ | TCGA | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation rewiring degron network | 0.3056 |
p.R181Q | TCGA-AJ-A3EK | UCEC | TCGA | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation rewiring degron network | 0.3056 |
p.R181Q | TCGA-AJ-A5DW | UCEC | TCGA | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation rewiring degron network | 0.3056 |
p.R181Q | TCGA-AN-A046 | BRCA | TCGA | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation rewiring degron network | 0.3056 |
p.R181Q | TCGA-D1-A16X | UCEC | TCGA | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation rewiring degron network | 0.3056 |
p.R181Q | TCGA-E2-A155 | BRCA | TCGA | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation rewiring degron network | 0.3056 |
p.R181Q | TCGA-EI-6917 | READ | TCGA | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation rewiring degron network | 0.3056 |
p.R181Q | TCGA-FU-A3HZ | CESC | TCGA | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation rewiring degron network | 0.3056 |
p.R181Q | TCGA-QF-A5YS | UCEC | TCGA | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation rewiring degron network | 0.3056 |
p.R181Q | DO1707 | BRCA | ICGC | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation rewiring degron network | 0.3056 |
p.R181Q | DO1285 | BRCA | ICGC | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation rewiring degron network | 0.3056 |
p.R181Q | DO6308 | CESC | ICGC | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation rewiring degron network | 0.3056 |
p.R181Q | DO7783 | COAD | ICGC | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation rewiring degron network | 0.3056 |
p.R181Q | DO8730 | COAD | ICGC | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation rewiring degron network | 0.3056 |
p.R181Q | DO222798 | COCA | ICGC | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation rewiring degron network | 0.3056 |
p.R181Q | DO229054 | LICA | ICGC | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation rewiring degron network | 0.3056 |
p.R181Q | DO36881 | READ | ICGC | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation rewiring degron network | 0.3056 |
p.R181Q | DO50075 | UCEC | ICGC | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation rewiring degron network | 0.3056 |
p.R181Q | DO41584 | UCEC | ICGC | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation rewiring degron network | 0.3056 |
p.R181Q | DO41799 | UCEC | ICGC | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation rewiring degron network | 0.3056 |
p.R181Q | DO52426 | UCEC | ICGC | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation rewiring degron network | 0.3056 |
p.R181Q | DO41379 | UCEC | ICGC | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation rewiring degron network | 0.3056 |
p.R181Q | SIDM01611 | Endometrial Carcinoma | GDSC | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation rewiring degron network | 0.3056 |
p.R181Q | SIDM01588 | Endometrial Carcinoma | GDSC | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation rewiring degron network | 0.3056 |
p.R181Q | ACH-000993 | Endometrial/Uterine Cancer | CCLE | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation rewiring degron network | 0.3056 |
p.R181Q | ACH-000996 | Endometrial/Uterine Cancer | CCLE | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation rewiring degron network | 0.3056 |
p.R181Q | ACH-001991 | Primary | CCLE | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation rewiring degron network | 0.3056 |
p.Q290E | TCGA-A8-A093 | BRCA | TCGA | NQTYSFSP | CBL_PTK | 289:296 | Mutation altering degron motif | 0.5633 |
p.Q290E | DO4161 | BRCA | ICGC | NQTYSFSP | CBL_PTK | 289:296 | Mutation altering degron motif | 0.5633 |
p.P174T | TCGA-AP-A1DK | UCEC | TCGA | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation rewiring degron network | 0.1111 |
p.P174T | DO42033 | UCEC | ICGC | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation rewiring degron network | 0.1111 |
p.N289K | TCGA-AX-A05Z | UCEC | TCGA | NQTYSFSP | CBL_PTK | 289:296 | Mutation altering degron motif | 0.6918 |
p.N289K | DO222798 | COCA | ICGC | NQTYSFSP | CBL_PTK | 289:296 | Mutation altering degron motif | 0.6918 |
p.N289K | DO40884 | UCEC | ICGC | NQTYSFSP | CBL_PTK | 289:296 | Mutation altering degron motif | 0.6918 |
p.S297F | TCGA-AY-A54L | COAD | TCGA | NQTYSFSP | CBL_PTK | 289:296 | Mutation blocking phosphorylation signal | 0.75 |
p.S297F | DO44091 | COAD | ICGC | NQTYSFSP | CBL_PTK | 289:296 | Mutation blocking phosphorylation signal | 0.75 |
p.P286T | TCGA-B5-A11E | UCEC | TCGA | NQTYSFSP | CBL_PTK | 289:296 | Mutation rewiring degron network | 0.25 |
p.P286T | DO41644 | UCEC | ICGC | NQTYSFSP | CBL_PTK | 289:296 | Mutation rewiring degron network | 0.25 |
p.R192K | TCGA-DK-A6AW | BLCA | TCGA | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation rewiring degron network | 0.2222 |
p.R192K | DO48566 | BLCA | ICGC | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation rewiring degron network | 0.2222 |
p.R183H | TCGA-FI-A2D5 | UCEC | TCGA | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation altering degron motif | 0.7133 |
p.R183H | DO9876 | COAD | ICGC | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation altering degron motif | 0.7133 |
p.R183H | DO41199 | UCEC | ICGC | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation altering degron motif | 0.7133 |
p.R183H | DO41331 | UCEC | ICGC | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation altering degron motif | 0.7133 |
p.R183H | SIDM00534 | Colorectal Carcinoma | GDSC | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation altering degron motif | 0.7133 |
p.R183H | ACH-000986 | Colon/Colorectal Cancer | CCLE | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation altering degron motif | 0.7133 |
p.R183H | HT-115 | large intestine | COSMIC | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation altering degron motif | 0.7133 |
p.R186G | DO50445 | ESAD | ICGC | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation altering degron motif | 0.6457 |
p.Q290K | DO228952 | LICA | ICGC | NQTYSFSP | CBL_PTK | 289:296 | Mutation altering degron motif | 0.5833 |
p.P283T | DO229024 | LICA | ICGC | NQTYSFSP | CBL_PTK | 289:296 | Mutation rewiring degron network | 0.1667 |
p.A289D | DO229027 | LICA | ICGC | NQTYSFSP | CBL_PTK | 289:296 | Mutation altering degron motif | 0.7793 |
p.A289G | DO23134 | LINC | ICGC | NQTYSFSP | CBL_PTK | 289:296 | Mutation altering degron motif | 0.754 |
p.Y292F | DO231906 | LINC | ICGC | NQTYSFSP | CBL_PTK | 289:296 | Mutation altering degron motif | 0.8639 |
p.Y292F | SIDM00435 | Acute Myeloid Leukemia | GDSC | NQTYSFSP | CBL_PTK | 289:296 | Mutation altering degron motif | 0.8639 |
p.Y292F | ACH-000369 | Leukemia | CCLE | NQTYSFSP | CBL_PTK | 289:296 | Mutation altering degron motif | 0.8639 |
p.Y292F | MOLM-16 | haematopoietic and lymphoid tissue | COSMIC | NQTYSFSP | CBL_PTK | 289:296 | Mutation altering degron motif | 0.8639 |
p.T290I | DO220239 | SARC | ICGC | NQTYSFSP | CBL_PTK | 289:296 | Mutation altering degron motif | 0.7078 |
p.D198Y | DO38635 | STAD | ICGC | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation rewiring degron network | 0.0556 |
p.E190D | DO229204 | THCA | ICGC | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation rewiring degron network | 0.2778 |
p.G282R | SIDM02057 | Colorectal Carcinoma | GDSC | NQTYSFSP | CBL_PTK | 289:296 | Mutation rewiring degron network | 0.1389 |
p.S293F | SIDM00080 | Melanoma | GDSC | NQTYSFSP | CBL_PTK | 289:296 | Mutation altering degron motif | 0.9093 |
p.S293F | ACH-000730 | Skin Cancer | CCLE | NQTYSFSP | CBL_PTK | 289:296 | Mutation altering degron motif | 0.9093 |
p.S293F | SK-MEL-5 | skin | COSMIC | NQTYSFSP | CBL_PTK | 289:296 | Mutation altering degron motif | 0.9093 |
p.I286V | SIDM01129 | Small Cell Lung Carcinoma | GDSC | NQTYSFSP | CBL_PTK | 289:296 | Mutation rewiring degron network | 0.25 |
p.I286V | NCI-H524 | lung | COSMIC | NQTYSFSP | CBL_PTK | 289:296 | Mutation rewiring degron network | 0.25 |
p.P185Q | ACH-000971 | Colon/Colorectal Cancer | CCLE | IRTPRAS | DEG_SCF_FBW7_1 | 182:188 | Mutation altering degron motif | 0.7035 |