p.H725R | TCGA-16-0846 | GBM | TCGA | AESSS | DEG_SPOP_SBC_1 | 712:716 | Mutation rewiring degron network | 0.0833 |
p.A468T | TCGA-18-5592 | LUSC | TCGA | PASSS | DEG_SPOP_SBC_1 | 477:481 | Mutation rewiring degron network | 0.0833 |
p.P1401L | TCGA-78-8662 | LUAD | TCGA | ASSSS | DEG_SPOP_SBC_1 | 1411:1415 | Mutation rewiring degron network | 0.0556 |
p.Y1682H | TCGA-85-8052 | LUSC | TCGA | VSSTS | DEG_SPOP_SBC_1 | 1675:1679 | Mutation rewiring degron network | 0.25 |
p.A1411T | TCGA-AJ-A3EK | UCEC | TCGA | ASSSS | DEG_SPOP_SBC_1 | 1411:1415 | Mutation altering degron motif | 0.7139 |
p.A1411T | TCGA-AX-A06F | UCEC | TCGA | ASSSS | DEG_SPOP_SBC_1 | 1411:1415 | Mutation altering degron motif | 0.7139 |
p.S559F | TCGA-AL-3472 | KIRP | TCGA | EDPSGAAVPEM | DEG_COP1_1 | 545:555 | Mutation rewiring degron network | 0.2222 |
p.S559F | SIDM01090 | Colorectal Carcinoma | GDSC | EDPSGAAVPEM | DEG_COP1_1 | 545:555 | Mutation rewiring degron network | 0.2222 |
p.S559F | RKO | large intestine | COSMIC | EDPSGAAVPEM | DEG_COP1_1 | 545:555 | Mutation rewiring degron network | 0.2222 |
p.R470H | TCGA-AP-A051 | UCEC | TCGA | PASSS | DEG_SPOP_SBC_1 | 477:481 | Mutation rewiring degron network | 0.1389 |
p.R470H | SIDM01314 | Colorectal Carcinoma | GDSC | PASSS | DEG_SPOP_SBC_1 | 477:481 | Mutation rewiring degron network | 0.1389 |
p.K483N | TCGA-AP-A0LM | UCEC | TCGA | PASSS | DEG_SPOP_SBC_1 | 477:481 | Mutation rewiring degron network | 0.2778 |
p.K483N | TCGA-BS-A0UF | UCEC | TCGA | PASSS | DEG_SPOP_SBC_1 | 477:481 | Mutation rewiring degron network | 0.2778 |
p.A1416T | TCGA-AP-A1DK | UCEC | TCGA | ASSSS | DEG_SPOP_SBC_1 | 1411:1415 | Mutation rewiring degron network | 0.3056 |
p.K558Q | TCGA-B5-A0JY | UCEC | TCGA | EDPSGAAVPEM | DEG_COP1_1 | 545:555 | Mutation substituting flanking lysine | 0.3611 |
p.E554D | TCGA-B5-A3FA | UCEC | TCGA | EDPSGAAVPEM | DEG_COP1_1 | 545:555 | Mutation altering degron motif | 0.5647 |
p.K561N | TCGA-BK-A6W3 | UCEC | TCGA | EDPSGAAVPEM | DEG_COP1_1 | 545:555 | Mutation substituting flanking lysine | 0.2778 |
p.A712S | TCGA-BR-7704 | STAD | TCGA | AESSS | DEG_SPOP_SBC_1 | 712:716 | Mutation altering degron motif | 0.7588 |
p.L486F | TCGA-BS-A0TE | UCEC | TCGA | PASSS | DEG_SPOP_SBC_1 | 477:481 | Mutation rewiring degron network | 0.1944 |
p.A468G | TCGA-CH-5748 | PRAD | TCGA | PASSS | DEG_SPOP_SBC_1 | 477:481 | Mutation rewiring degron network | 0.0833 |
p.S702Y | TCGA-CM-6171 | COAD | TCGA | AESSS | DEG_SPOP_SBC_1 | 712:716 | Mutation rewiring degron network | 0.0556 |
p.H1668R | TCGA-CV-6956 | HNSC | TCGA | VSSTS | DEG_SPOP_SBC_1 | 1675:1679 | Mutation rewiring degron network | 0.1389 |
p.S1673F | TCGA-DD-A4NN | LIHC | TCGA | VSSTS | DEG_SPOP_SBC_1 | 1675:1679 | Mutation rewiring degron network | 0.2778 |
p.V1667F | TCGA-EE-A2MG | SKCM | TCGA | VSSTS | DEG_SPOP_SBC_1 | 1675:1679 | Mutation rewiring degron network | 0.1111 |
p.V1667F | DO37421 | SKCM | ICGC | VSSTS | DEG_SPOP_SBC_1 | 1675:1679 | Mutation rewiring degron network | 0.1111 |
p.S1679L | TCGA-EO-A22U | UCEC | TCGA | VSSTS | DEG_SPOP_SBC_1 | 1675:1679 | Mutation altering degron motif | 0.7667 |
p.K1688T | TCGA-EO-A3AV | UCEC | TCGA | VSSTS | DEG_SPOP_SBC_1 | 1675:1679 | Mutation substituting flanking lysine | 0.1944 |
p.S1670T | TCGA-V5-A7RB | ESCA | TCGA | VSSTS | DEG_SPOP_SBC_1 | 1675:1679 | Mutation rewiring degron network | 0.1944 |
p.S1670Y | TCGA-V5-A7RB | ESCA | TCGA | VSSTS | DEG_SPOP_SBC_1 | 1675:1679 | Mutation rewiring degron network | 0.1944 |
p.G476C | TCGA-ZS-A9CD | LIHC | TCGA | PASSS | DEG_SPOP_SBC_1 | 477:481 | Mutation rewiring degron network | 0.3056 |
p.S1417C | DO2401 | BRCA | ICGC | ASSSS | DEG_SPOP_SBC_1 | 1411:1415 | Mutation rewiring degron network | 0.2778 |
p.S1419I | DO4780 | BRCA | ICGC | ASSSS | DEG_SPOP_SBC_1 | 1411:1415 | Mutation substituting flanking lysine | 0.3333 |
p.R723Q | DO52709 | CLLE | ICGC | AESSS | DEG_SPOP_SBC_1 | 712:716 | Mutation rewiring degron network | 0.1389 |
p.R723Q | DO41014 | UCEC | ICGC | AESSS | DEG_SPOP_SBC_1 | 712:716 | Mutation rewiring degron network | 0.1389 |
p.T726A | DO10300 | COAD | ICGC | AESSS | DEG_SPOP_SBC_1 | 712:716 | Mutation rewiring degron network | 0.0556 |
p.E490D | DO8842 | COAD | ICGC | PASSS | DEG_SPOP_SBC_1 | 477:481 | Mutation rewiring degron network | 0.0833 |
p.E490D | DO41752 | UCEC | ICGC | PASSS | DEG_SPOP_SBC_1 | 477:481 | Mutation rewiring degron network | 0.0833 |
p.K1689N | DO227709 | COCA | ICGC | VSSTS | DEG_SPOP_SBC_1 | 1675:1679 | Mutation rewiring degron network | 0.0556 |
p.Q468H | DO229013 | COCA | ICGC | PASSS | DEG_SPOP_SBC_1 | 477:481 | Mutation rewiring degron network | 0.0833 |
p.Q468H | DO229016 | COCA | ICGC | PASSS | DEG_SPOP_SBC_1 | 477:481 | Mutation rewiring degron network | 0.0833 |
p.Q468H | DO229005 | COCA | ICGC | PASSS | DEG_SPOP_SBC_1 | 477:481 | Mutation rewiring degron network | 0.0833 |
p.Q468H | DO229480 | LAML | ICGC | PASSS | DEG_SPOP_SBC_1 | 477:481 | Mutation rewiring degron network | 0.0833 |
p.Q468H | DO229505 | LAML | ICGC | PASSS | DEG_SPOP_SBC_1 | 477:481 | Mutation rewiring degron network | 0.0833 |
p.Q468H | DO228947 | LICA | ICGC | PASSS | DEG_SPOP_SBC_1 | 477:481 | Mutation rewiring degron network | 0.0833 |
p.Q468H | DO230931 | LUSC | ICGC | PASSS | DEG_SPOP_SBC_1 | 477:481 | Mutation rewiring degron network | 0.0833 |
p.A558V | DO222440 | ESCA | ICGC | EDPSGAAVPEM | DEG_COP1_1 | 545:555 | Mutation substituting flanking lysine | 0.3611 |
p.H702R | DO13635 | GBM | ICGC | AESSS | DEG_SPOP_SBC_1 | 712:716 | Mutation rewiring degron network | 0.0556 |
p.N485Y | DO16486 | KIRC | ICGC | PASSS | DEG_SPOP_SBC_1 | 477:481 | Mutation rewiring degron network | 0.2222 |
p.S536F | DO20923 | KIRP | ICGC | EDPSGAAVPEM | DEG_COP1_1 | 545:555 | Mutation rewiring degron network | 0.0833 |
p.S536F | RKO | large intestine | COSMIC | EDPSGAAVPEM | DEG_COP1_1 | 545:555 | Mutation rewiring degron network | 0.0833 |
p.A1667S | DO228952 | LICA | ICGC | VSSTS | DEG_SPOP_SBC_1 | 1675:1679 | Mutation rewiring degron network | 0.1111 |
p.G716W | DO229022 | LICA | ICGC | AESSS | DEG_SPOP_SBC_1 | 712:716 | Mutation altering degron motif | 0.7825 |
p.A479S | DO229022 | LICA | ICGC | PASSS | DEG_SPOP_SBC_1 | 477:481 | Mutation altering degron motif | 0.7588 |
p.S1681I | DO229026 | LICA | ICGC | VSSTS | DEG_SPOP_SBC_1 | 1675:1679 | Mutation rewiring degron network | 0.2778 |
p.S1406I | DO229009 | LICA | ICGC | ASSSS | DEG_SPOP_SBC_1 | 1411:1415 | Mutation rewiring degron network | 0.1944 |
p.A721S | DO25113 | LUAD | ICGC | AESSS | DEG_SPOP_SBC_1 | 712:716 | Mutation rewiring degron network | 0.1944 |
p.Q1670H | DO45319 | LUAD | ICGC | VSSTS | DEG_SPOP_SBC_1 | 1675:1679 | Mutation rewiring degron network | 0.1944 |
p.K705E | DO228600 | MALY | ICGC | AESSS | DEG_SPOP_SBC_1 | 712:716 | Mutation rewiring degron network | 0.1389 |
p.S1413F | DO220907 | MELA | ICGC | ASSSS | DEG_SPOP_SBC_1 | 1411:1415 | Mutation altering degron motif | 0.7982 |
p.G707E | DO46657 | PAAD | ICGC | AESSS | DEG_SPOP_SBC_1 | 712:716 | Mutation rewiring degron network | 0.1944 |
p.R725W | DO35140 | PACA | ICGC | AESSS | DEG_SPOP_SBC_1 | 712:716 | Mutation rewiring degron network | 0.0833 |
p.S480T | DO51537 | PACA | ICGC | PASSS | DEG_SPOP_SBC_1 | 477:481 | Mutation altering degron motif | 0.6005 |
p.G707A | DO230637 | PRAD | ICGC | AESSS | DEG_SPOP_SBC_1 | 712:716 | Mutation rewiring degron network | 0.1944 |
p.R722Q | DO36262 | PRAD | ICGC | AESSS | DEG_SPOP_SBC_1 | 712:716 | Mutation rewiring degron network | 0.1667 |
p.K553N | DO36556 | READ | ICGC | EDPSGAAVPEM | DEG_COP1_1 | 545:555 | Mutation altering degron motif | 0.6918 |
p.M1675V | DO218859 | SKCA | ICGC | VSSTS | DEG_SPOP_SBC_1 | 1675:1679 | Mutation altering degron motif | 0.7208 |
p.P544S | DO47569 | SKCM | ICGC | EDPSGAAVPEM | DEG_COP1_1 | 545:555 | Mutation rewiring degron network | 0.3056 |
p.P565L | DO47989 | STAD | ICGC | EDPSGAAVPEM | DEG_COP1_1 | 545:555 | Mutation rewiring degron network | 0.0556 |
p.K538N | DO50076 | UCEC | ICGC | EDPSGAAVPEM | DEG_COP1_1 | 545:555 | Mutation rewiring degron network | 0.1389 |
p.S1417Y | DO42057 | UCEC | ICGC | ASSSS | DEG_SPOP_SBC_1 | 1411:1415 | Mutation rewiring degron network | 0.2778 |
p.A479T | DO42033 | UCEC | ICGC | PASSS | DEG_SPOP_SBC_1 | 477:481 | Mutation altering degron motif | 0.7139 |
p.K535Q | DO43041 | UCEC | ICGC | EDPSGAAVPEM | DEG_COP1_1 | 545:555 | Mutation rewiring degron network | 0.0556 |
p.V490A | DO42600 | UCEC | ICGC | PASSS | DEG_SPOP_SBC_1 | 477:481 | Mutation rewiring degron network | 0.0833 |
p.R473W | DO41235 | UCEC | ICGC | PASSS | DEG_SPOP_SBC_1 | 477:481 | Mutation rewiring degron network | 0.2222 |
p.R473W | NCI-H1435 | lung | COSMIC | PASSS | DEG_SPOP_SBC_1 | 477:481 | Mutation rewiring degron network | 0.2222 |
p.R473Q | DO41235 | UCEC | ICGC | PASSS | DEG_SPOP_SBC_1 | 477:481 | Mutation rewiring degron network | 0.2222 |
p.D1415N | DO42713 | UCEC | ICGC | ASSSS | DEG_SPOP_SBC_1 | 1411:1415 | Mutation altering degron motif | 0.6932 |
p.S562C | DO41325 | UCEC | ICGC | EDPSGAAVPEM | DEG_COP1_1 | 545:555 | Mutation rewiring degron network | 0.1389 |
p.P477T | SIDM02050 | Colorectal Carcinoma | GDSC | PASSS | DEG_SPOP_SBC_1 | 477:481 | Mutation altering degron motif | 0.7031 |
p.S548N | SIDM00499 | Prostate Carcinoma | GDSC | EDPSGAAVPEM | DEG_COP1_1 | 545:555 | Mutation altering degron motif | 0.818 |
p.S548N | 22RV1 | prostate | COSMIC | EDPSGAAVPEM | DEG_COP1_1 | 545:555 | Mutation altering degron motif | 0.818 |
p.T474I | SIDM00629 | Breast Carcinoma | GDSC | PASSS | DEG_SPOP_SBC_1 | 477:481 | Mutation rewiring degron network | 0.25 |
p.T474I | MDA-MB-436 | breast | COSMIC | PASSS | DEG_SPOP_SBC_1 | 477:481 | Mutation rewiring degron network | 0.25 |
p.A563S | SIDM00277 | Acute Myeloid Leukemia | GDSC | EDPSGAAVPEM | DEG_COP1_1 | 545:555 | Mutation rewiring degron network | 0.1111 |
p.A563S | ACH-000198 | Leukemia | CCLE | EDPSGAAVPEM | DEG_COP1_1 | 545:555 | Mutation rewiring degron network | 0.1111 |
p.A563S | EoL-1-cell | haematopoietic and lymphoid tissue | COSMIC | EDPSGAAVPEM | DEG_COP1_1 | 545:555 | Mutation rewiring degron network | 0.1111 |
p.A1416E | SIDM01028 | Esophageal Squamous Cell Carcinoma | GDSC | ASSSS | DEG_SPOP_SBC_1 | 1411:1415 | Mutation rewiring degron network | 0.3056 |
p.A1416E | KYSE-410 | oesophagus | COSMIC | ASSSS | DEG_SPOP_SBC_1 | 1411:1415 | Mutation rewiring degron network | 0.3056 |
p.G1423S | SIDM01158 | Squamous Cell Lung Carcinoma | GDSC | ASSSS | DEG_SPOP_SBC_1 | 1411:1415 | Mutation rewiring degron network | 0.1111 |
p.G1423S | SW900 | lung | COSMIC | ASSSS | DEG_SPOP_SBC_1 | 1411:1415 | Mutation rewiring degron network | 0.1111 |
p.G708W | SIDM01617 | Endometrial Carcinoma | GDSC | AESSS | DEG_SPOP_SBC_1 | 712:716 | Mutation rewiring degron network | 0.2222 |
p.L710F | ACH-000259 | Neuroblastoma | CCLE | AESSS | DEG_SPOP_SBC_1 | 712:716 | Mutation rewiring degron network | 0.2778 |
p.L710F | KELLY | autonomic ganglia | COSMIC | AESSS | DEG_SPOP_SBC_1 | 712:716 | Mutation rewiring degron network | 0.2778 |
p.S472F | ACH-000943 | Colon/Colorectal Cancer | CCLE | PASSS | DEG_SPOP_SBC_1 | 477:481 | Mutation rewiring degron network | 0.1944 |
p.S472F | RKO | large intestine | COSMIC | PASSS | DEG_SPOP_SBC_1 | 477:481 | Mutation rewiring degron network | 0.1944 |
p.R1675H | ACH-001377 | Pancreatic Cancer | CCLE | VSSTS | DEG_SPOP_SBC_1 | 1675:1679 | Mutation altering degron motif | 0.8244 |
p.S550F | ACH-001550 | Skin Cancer | CCLE | EDPSGAAVPEM | DEG_COP1_1 | 545:555 | Mutation altering degron motif | 0.7982 |
p.S550F | MCC13 | skin | COSMIC | EDPSGAAVPEM | DEG_COP1_1 | 545:555 | Mutation altering degron motif | 0.7982 |
p.V1683I | ACH-001664 | Gastric Cancer | CCLE | VSSTS | DEG_SPOP_SBC_1 | 1675:1679 | Mutation rewiring degron network | 0.2222 |
p.R705C | ACH-001719 | Ovarian Cancer | CCLE | AESSS | DEG_SPOP_SBC_1 | 712:716 | Mutation rewiring degron network | 0.1389 |
p.G722D | ACH-002154 | Lung Cancer | CCLE | AESSS | DEG_SPOP_SBC_1 | 712:716 | Mutation rewiring degron network | 0.1667 |
p.G722D | LB647-SCLC | lung | COSMIC | AESSS | DEG_SPOP_SBC_1 | 712:716 | Mutation rewiring degron network | 0.1667 |
p.S562N | DU-145 | prostate | COSMIC | EDPSGAAVPEM | DEG_COP1_1 | 545:555 | Mutation rewiring degron network | 0.1389 |
p.G707R | MMAC-SF | skin | COSMIC | AESSS | DEG_SPOP_SBC_1 | 712:716 | Mutation rewiring degron network | 0.1944 |
p.T704I | SCH | stomach | COSMIC | AESSS | DEG_SPOP_SBC_1 | 712:716 | Mutation rewiring degron network | 0.1111 |
p.R706Q | GP5d | large intestine | COSMIC | AESSS | DEG_SPOP_SBC_1 | 712:716 | Mutation rewiring degron network | 0.1667 |
p.A540S | EoL-1-cell | haematopoietic and lymphoid tissue | COSMIC | EDPSGAAVPEM | DEG_COP1_1 | 545:555 | Mutation substituting flanking lysine | 0.3056 |
p.A479E | KYSE-410 | oesophagus | COSMIC | PASSS | DEG_SPOP_SBC_1 | 477:481 | Mutation altering degron motif | 0.7701 |
p.A476S | EoL-1-cell | haematopoietic and lymphoid tissue | COSMIC | PASSS | DEG_SPOP_SBC_1 | 477:481 | Mutation rewiring degron network | 0.3056 |
p.R722W | SUP-HD1 | haematopoietic and lymphoid tissue | COSMIC | AESSS | DEG_SPOP_SBC_1 | 712:716 | Mutation rewiring degron network | 0.1667 |
p.T1685A | HCT-116 | large intestine | COSMIC | VSSTS | DEG_SPOP_SBC_1 | 1675:1679 | Mutation rewiring degron network | 0.1667 |
p.G486S | SW900 | lung | COSMIC | PASSS | DEG_SPOP_SBC_1 | 477:481 | Mutation rewiring degron network | 0.1944 |
p.D709Y | EFO-21 | ovary | COSMIC | AESSS | DEG_SPOP_SBC_1 | 712:716 | Mutation rewiring degron network | 0.25 |