DegronMD - Q8IZS6(DYNLT2)

DYNLT2

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P27S	TCGA-BR-6452	STAD	TCGA	PVTPRKE	DEG_SCF_FBW7_2	24:30	Mutation altering degron motif	0.6752
p.P27S	DO38404	STAD	ICGC	PVTPRKE	DEG_SCF_FBW7_2	24:30	Mutation altering degron motif	0.6752
p.R6L	TCGA-D3-A2JP	SKCM	TCGA	PIQTPNQT	DEG_SCF_FBW7_1	12:19	Mutation rewiring degron network	0.1667
p.R6L	DO47407	SKCM	ICGC	PIQTPNQT	DEG_SCF_FBW7_1	12:19	Mutation rewiring degron network	0.1667
p.E37Q	TCGA-TS-A7OZ	MESO	TCGA	PVTPRKE	DEG_SCF_FBW7_2	24:30	Mutation rewiring degron network	0.1389
p.Q18H	TCGA-XF-A8HF	BLCA	TCGA	PIQTPNQT	DEG_SCF_FBW7_1	12:19	Mutation altering degron motif	0.647
p.Q18H	DO49800	BLCA	ICGC	PIQTPNQT	DEG_SCF_FBW7_1	12:19	Mutation altering degron motif	0.647
p.Q18H	DO231772	LINC	ICGC	PIQTPNQT	DEG_SCF_FBW7_1	12:19	Mutation altering degron motif	0.647
p.T26A	DO233935	GACA	ICGC	PVTPRKE	DEG_SCF_FBW7_2	24:30	Mutation altering degron motif	0.7139
p.V25L	DO23248	LINC	ICGC	PVTPRKE	DEG_SCF_FBW7_2	24:30	Mutation altering degron motif	0.5654
p.Q14H	DO220841	MELA	ICGC	PIQTPNQT	DEG_SCF_FBW7_1	12:19	Mutation altering degron motif	0.647
p.Q14H	ACH-000997	Colon/Colorectal Cancer	CCLE	PIQTPNQT	DEG_SCF_FBW7_1	12:19	Mutation altering degron motif	0.647
p.Q14H	HCT-15	large intestine	COSMIC	PIQTPNQT	DEG_SCF_FBW7_1	12:19	Mutation altering degron motif	0.647
p.K3Q	ACH-000427	Gastric Cancer	CCLE	PIQTPNQT	DEG_SCF_FBW7_1	12:19	Mutation substituting flanking lysine	0.1944
p.K3Q	NCI-N87	stomach	COSMIC	PIQTPNQT	DEG_SCF_FBW7_1	12:19	Mutation substituting flanking lysine	0.1944

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*NOTE: the Kaplan plots were collected from OncoLnc