DegronMD - Q8NCW6(GALNT11)

GALNT11

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R482L	TCGA-17-Z052	LUAD	TCGA	QRGRLYHLQ	DEG_APCC_DBOX_1	481:489	Mutation altering degron motif	0.8428
p.R482L	TCGA-17-Z052	LUAD	TCGA	LQRGR	SCF_FBXL2	480:484	Mutation altering degron motif	0.8428
p.K492R	TCGA-AA-3811	COAD	TCGA	QRGRLYHLQ	DEG_APCC_DBOX_1	481:489	Mutation substituting flanking lysine	0.3611
p.K492R	TCGA-AA-3811	COAD	TCGA	LQRGR	SCF_FBXL2	480:484	Mutation substituting flanking lysine	0.2222
p.K492R	DO7962	COAD	ICGC	QRGRLYHLQ	DEG_APCC_DBOX_1	481:489	Mutation substituting flanking lysine	0.3611
p.K492R	DO7962	COAD	ICGC	LQRGR	SCF_FBXL2	480:484	Mutation substituting flanking lysine	0.2222
p.G473V	DO228948	LICA	ICGC	QRGRLYHLQ	DEG_APCC_DBOX_1	481:489	Mutation rewiring degron network	0.1111
p.G473V	DO228948	LICA	ICGC	LQRGR	SCF_FBXL2	480:484	Mutation rewiring degron network	0.1389
p.Q497K	DO35723	PBCA	ICGC	QRGRLYHLQ	DEG_APCC_DBOX_1	481:489	Mutation rewiring degron network	0.1111
p.L488V	ACH-002397	Thyroid Cancer	CCLE	QRGRLYHLQ	DEG_APCC_DBOX_1	481:489	Mutation altering degron motif	0.5654
p.L488V	KMH-2	thyroid	COSMIC	QRGRLYHLQ	DEG_APCC_DBOX_1	481:489	Mutation altering degron motif	0.5654

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*NOTE: the Kaplan plots were collected from OncoLnc