DegronMD - Q8ND30(PPFIBP2)

PPFIBP2

Please click HERE for better display.

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E792Q	TCGA-34-5240	LUSC	TCGA	PAYTPLTT	DEG_SCF_FBW7_1	800:807	Mutation rewiring degron network	0.1111
p.Y802C	TCGA-AA-A02R	COAD	TCGA	PAYTPLTT	DEG_SCF_FBW7_1	800:807	Mutation altering degron motif	0.7087
p.P804Q	TCGA-DU-6392	LGG	TCGA	PAYTPLTT	DEG_SCF_FBW7_1	800:807	Mutation altering degron motif	0.7035
p.P804Q	TCGA-DU-6392	LGG	TCGA	PLTTT	DEG_SPOP_SBC_1	804:808	Mutation altering degron motif	0.7035
p.E795Q	TCGA-NK-A5CR	LUSC	TCGA	PAYTPLTT	DEG_SCF_FBW7_1	800:807	Mutation rewiring degron network	0.1944
p.E795Q	TCGA-NK-A5CR	LUSC	TCGA	PLTTT	DEG_SPOP_SBC_1	804:808	Mutation rewiring degron network	0.0833
p.R812Q	SIDM00473	Oral Cavity Carcinoma	GDSC	PAYTPLTT	DEG_SCF_FBW7_1	800:807	Mutation rewiring degron network	0.1944
p.R812Q	SIDM00473	Oral Cavity Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	804:808	Mutation rewiring degron network	0.2222
p.A798S	SIDM01574	Plasma Cell Myeloma	GDSC	PAYTPLTT	DEG_SCF_FBW7_1	800:807	Mutation rewiring degron network	0.2778
p.A798S	SIDM01574	Plasma Cell Myeloma	GDSC	PLTTT	DEG_SPOP_SBC_1	804:808	Mutation rewiring degron network	0.1667
p.A798S	SIDM01391	Neuroblastoma	GDSC	PAYTPLTT	DEG_SCF_FBW7_1	800:807	Mutation rewiring degron network	0.2778
p.A798S	SIDM01391	Neuroblastoma	GDSC	PLTTT	DEG_SPOP_SBC_1	804:808	Mutation rewiring degron network	0.1667

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc