DegronMD - Q8TD94(KLF14)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A159T	TCGA-AZ-4315	COAD	TCGA	ESSSDAPAVPSA	DEG_COP1_1	142:153	Mutation rewiring degron network	0.1667
p.A159T	DO8842	COAD	ICGC	ESSSDAPAVPSA	DEG_COP1_1	142:153	Mutation rewiring degron network	0.1667
p.P148T	DO229045	LICA	ICGC	ESSSDAPAVPSA	DEG_COP1_1	142:153	Mutation altering degron motif	0.5919
p.D146Y	DO23124	LINC	ICGC	ESSSDAPAVPSA	DEG_COP1_1	142:153	Mutation altering degron motif	0.7325
p.P141A	DO50842	LIRI	ICGC	PESSS	DEG_SPOP_SBC_1	141:145	Mutation altering degron motif	0.6392
p.A132T	DO232761	PBCA	ICGC	ESSSDAPAVPSA	DEG_COP1_1	142:153	Mutation rewiring degron network	0.0556
p.A132T	DO232761	PBCA	ICGC	VQTPCSE	DEG_SCF_FBW7_2	122:128	Mutation rewiring degron network	0.2222
p.A132T	DO232761	PBCA	ICGC	PESSS	DEG_SPOP_SBC_1	141:145	Mutation rewiring degron network	0.0833
p.T124P	DO218862	SKCA	ICGC	VQTPCSE	DEG_SCF_FBW7_2	122:128	Mutation altering degron motif	0.7031
p.D116N	SIDM01016	T-Lymphoblastic Leukemia	GDSC	VQTPCSE	DEG_SCF_FBW7_2	122:128	Mutation rewiring degron network	0.1667
p.P151T	SIDM00163	Biliary Tract Carcinoma	GDSC	ESSSDAPAVPSA	DEG_COP1_1	142:153	Mutation altering degron motif	0.7031
p.P151T	SIDM01446	Glioblastoma	GDSC	ESSSDAPAVPSA	DEG_COP1_1	142:153	Mutation altering degron motif	0.7031
p.P151T	SIDM01451	Pancreatic Carcinoma	GDSC	ESSSDAPAVPSA	DEG_COP1_1	142:153	Mutation altering degron motif	0.7031
p.P131S	ACH-001956	Bone Cancer	CCLE	VQTPCSE	DEG_SCF_FBW7_2	122:128	Mutation rewiring degron network	0.25
p.P131S	ACH-001956	Bone Cancer	CCLE	PESSS	DEG_SPOP_SBC_1	141:145	Mutation rewiring degron network	0.0556
p.G158A	ACH-002029	Head and Neck Cancer	CCLE	ESSSDAPAVPSA	DEG_COP1_1	142:153	Mutation rewiring degron network	0.1944

Kaplan plot for KLF14 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

KLF14

UniProt ID: Q8TD94

Entrez ID: 136259

Protein name: Krueppel-like factor 14 (Basic transcription element-binding protein 5) (BTE-binding protein 5) (Transcription factor BTEB5)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for KLF14 in