DegronMD - Q93008(USP9X)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P58Q	TCGA-18-3410	LUSC	TCGA	PATPPDE	DEG_SCF_FBW7_2	44:50	Mutation rewiring degron network	0.1111
p.P58Q	DO26456	LUSC	ICGC	PATPPDE	DEG_SCF_FBW7_2	44:50	Mutation rewiring degron network	0.1111
p.H993N	TCGA-B5-A1MR	UCEC	TCGA	NHGNHYSDGP	CBL_PTK	989:998	Mutation altering degron motif	0.6312
p.H993N	DO41758	UCEC	ICGC	NHGNHYSDGP	CBL_PTK	989:998	Mutation altering degron motif	0.6312
p.P976H	TCGA-D3-A2JL	SKCM	TCGA	PDSSS	DEG_SPOP_SBC_1	976:980	Mutation altering degron motif	0.7694
p.P976H	DO47278	SKCM	ICGC	PDSSS	DEG_SPOP_SBC_1	976:980	Mutation altering degron motif	0.7694
p.A56V	TCGA-DQ-5625	HNSC	TCGA	PATPPDE	DEG_SCF_FBW7_2	44:50	Mutation rewiring degron network	0.1667
p.A56V	DO15414	HNSC	ICGC	PATPPDE	DEG_SCF_FBW7_2	44:50	Mutation rewiring degron network	0.1667
p.P44T	TCGA-EE-A3AA	SKCM	TCGA	PATPPDE	DEG_SCF_FBW7_2	44:50	Mutation altering degron motif	0.7031
p.P44T	DO37571	SKCM	ICGC	PATPPDE	DEG_SCF_FBW7_2	44:50	Mutation altering degron motif	0.7031
p.E1001G	DO228404	BRCA	ICGC	NHGNHYSDGP	CBL_PTK	989:998	Mutation rewiring degron network	0.25
p.G991V	DO229018	LICA	ICGC	NHGNHYSDGP	CBL_PTK	989:998	Mutation altering degron motif	0.6421
p.C1005F	DO229018	LICA	ICGC	NHGNHYSDGP	CBL_PTK	989:998	Mutation rewiring degron network	0.1389
p.C1005F	DO229036	LICA	ICGC	NHGNHYSDGP	CBL_PTK	989:998	Mutation rewiring degron network	0.1389
p.E50D	DO229029	LICA	ICGC	PATPPDE	DEG_SCF_FBW7_2	44:50	Mutation altering degron motif	0.6758
p.P44L	DO33208	PACA	ICGC	PATPPDE	DEG_SCF_FBW7_2	44:50	Mutation altering degron motif	0.6471
p.P987L	DO218850	SKCA	ICGC	PDSSS	DEG_SPOP_SBC_1	976:980	Mutation rewiring degron network	0.1389
p.P987L	DO218850	SKCA	ICGC	NHGNHYSDGP	CBL_PTK	989:998	Mutation rewiring degron network	0.2778
p.Q51E	SIDM01624	Bladder Carcinoma	GDSC	PATPPDE	DEG_SCF_FBW7_2	44:50	Mutation rewiring degron network	0.3056
p.Q51E	ACH-000026	Bladder Cancer	CCLE	PATPPDE	DEG_SCF_FBW7_2	44:50	Mutation rewiring degron network	0.3056

Kaplan plot for USP9X in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

USP9X

UniProt ID: Q93008

Entrez ID: 8239

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for USP9X in