DegronMD - Q96AQ8(MCUR1)

MCUR1

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R13H	DO229268	THCA	ICGC	GRQRLLFLP	DEG_APCC_DBOX_1	16:24	Mutation rewiring degron network	0.25
p.P31R	SIDM00773	Non-Cancerous	GDSC	GRQRLLFLP	DEG_APCC_DBOX_1	16:24	Mutation rewiring degron network	0.1389
p.P31R	SIDM00773	Non-Cancerous	GDSC	ARRCLSALS	DEG_APCC_DBOX_1	38:46	Mutation rewiring degron network	0.1389
p.P31R	ACH-000691	Breast Cancer	CCLE	GRQRLLFLP	DEG_APCC_DBOX_1	16:24	Mutation rewiring degron network	0.1389
p.P31R	ACH-000691	Breast Cancer	CCLE	ARRCLSALS	DEG_APCC_DBOX_1	38:46	Mutation rewiring degron network	0.1389
p.G32A	SIDM01259	B-Lymphoblastic Leukemia	GDSC	GRQRLLFLP	DEG_APCC_DBOX_1	16:24	Mutation rewiring degron network	0.1111
p.G32A	SIDM01259	B-Lymphoblastic Leukemia	GDSC	ARRCLSALS	DEG_APCC_DBOX_1	38:46	Mutation rewiring degron network	0.1667
p.G32A	ACH-001669	Leukemia	CCLE	GRQRLLFLP	DEG_APCC_DBOX_1	16:24	Mutation rewiring degron network	0.1111
p.G32A	ACH-001669	Leukemia	CCLE	ARRCLSALS	DEG_APCC_DBOX_1	38:46	Mutation rewiring degron network	0.1667
p.R55G	SIDM00271	Gastric Carcinoma	GDSC	ARRCLSALS	DEG_APCC_DBOX_1	38:46	Mutation rewiring degron network	0.0833
p.R55G	ACH-000351	Gastric Cancer	CCLE	ARRCLSALS	DEG_APCC_DBOX_1	38:46	Mutation rewiring degron network	0.0833
p.A38T	ACH-000870	Lung Cancer	CCLE	ARRCLSALS	DEG_APCC_DBOX_1	38:46	Mutation altering degron motif	0.6028

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*NOTE: the Kaplan plots were collected from OncoLnc