DegronMD - Q96ES7(SGF29)

SGF29

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R60C	SIDM01293	Colorectal Carcinoma	GDSC	YRTKLRGLY	DEG_APCC_DBOX_1	55:63	Mutation altering degron motif	0.719
p.R60C	SIDM01088	Endometrial Carcinoma	GDSC	YRTKLRGLY	DEG_APCC_DBOX_1	55:63	Mutation altering degron motif	0.719
p.R60C	RL95-2	endometrium	COSMIC	YRTKLRGLY	DEG_APCC_DBOX_1	55:63	Mutation altering degron motif	0.719
p.R115H	SIDM01058	B-Cell Non-Hodgkin's Lymphoma	GDSC	RRGVLMTLL	DEG_APCC_DBOX_1	115:123	Mutation altering degron motif	0.7133
p.R115H	GRANTA-519	haematopoietic and lymphoid tissue	COSMIC	RRGVLMTLL	DEG_APCC_DBOX_1	115:123	Mutation altering degron motif	0.7133
p.K112N	SIDM00099	Mesothelioma	GDSC	RRGVLMTLL	DEG_APCC_DBOX_1	115:123	Mutation substituting flanking lysine	0.3611
p.K112N	H2722	pleura	COSMIC	RRGVLMTLL	DEG_APCC_DBOX_1	115:123	Mutation substituting flanking lysine	0.3611
p.R60H	SIDM00118	Colorectal Carcinoma	GDSC	YRTKLRGLY	DEG_APCC_DBOX_1	55:63	Mutation altering degron motif	0.7133
p.R60H	HCC2998	large intestine	COSMIC	YRTKLRGLY	DEG_APCC_DBOX_1	55:63	Mutation altering degron motif	0.7133
p.A66T	SIDM01618	B-Lymphoblastic Leukemia	GDSC	YRTKLRGLY	DEG_APCC_DBOX_1	55:63	Mutation rewiring degron network	0.25

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*NOTE: the Kaplan plots were collected from OncoLnc