DegronMD - Q96QU1(PCDH15)

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P161T	TCGA-77-8009	LUSC	TCGA	LTPVGT	DEG_SCF_FBW7_1	159:164	Mutation altering degron motif	0.7031
p.T155I	TCGA-94-A4VJ	LUSC	TCGA	LTPVGT	DEG_SCF_FBW7_1	159:164	Mutation rewiring degron network	0.2222
p.T165I	TCGA-A5-A0G1	UCEC	TCGA	LTPVGT	DEG_SCF_FBW7_1	159:164	Mutation rewiring degron network	0.3056
p.P1761H	TCGA-A6-3810	COAD	TCGA	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.2222
p.I1755V	TCGA-AA-3966	COAD	TCGA	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.0556
p.F170Y	TCGA-AG-A002	READ	TCGA	LTPVGT	DEG_SCF_FBW7_1	159:164	Mutation rewiring degron network	0.1667
p.V156M	TCGA-BK-A0C9	UCEC	TCGA	LTPVGT	DEG_SCF_FBW7_1	159:164	Mutation rewiring degron network	0.25
p.V156M	DO41253	UCEC	ICGC	LTPVGT	DEG_SCF_FBW7_1	159:164	Mutation rewiring degron network	0.25
p.P1775S	TCGA-D3-A8GL	SKCM	TCGA	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation altering degron motif	0.6752
p.G169E	TCGA-D3-A8GL	SKCM	TCGA	LTPVGT	DEG_SCF_FBW7_1	159:164	Mutation rewiring degron network	0.1944
p.G169E	TCGA-W3-AA1V	SKCM	TCGA	LTPVGT	DEG_SCF_FBW7_1	159:164	Mutation rewiring degron network	0.1944
p.G169R	TCGA-DA-A95Y	SKCM	TCGA	LTPVGT	DEG_SCF_FBW7_1	159:164	Mutation rewiring degron network	0.1944
p.P1785H	TCGA-DF-A2KU	UCEC	TCGA	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.0833
p.P1769H	TCGA-DF-A2KU	UCEC	TCGA	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation altering degron motif	0.6583
p.Y152H	TCGA-DI-A1BU	UCEC	TCGA	LTPVGT	DEG_SCF_FBW7_1	159:164	Mutation rewiring degron network	0.1389
p.G163D	TCGA-EB-A3XF	SKCM	TCGA	LTPVGT	DEG_SCF_FBW7_1	159:164	Mutation altering degron motif	0.6087
p.G163D	DO37437	SKCM	ICGC	LTPVGT	DEG_SCF_FBW7_1	159:164	Mutation altering degron motif	0.6087
p.S1784Y	TCGA-EI-6917	READ	TCGA	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.1111
p.P1757S	TCGA-FR-A8YC	SKCM	TCGA	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.1111
p.G163C	TCGA-LN-A49Y	ESCA	TCGA	LTPVGT	DEG_SCF_FBW7_1	159:164	Mutation altering degron motif	0.6489
p.P1757T	TCGA-NJ-A4YF	LUAD	TCGA	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.1111
p.A1763D	TCGA-O2-A52Q	LUSC	TCGA	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.2778
p.A1763D	NCI-H1105	lung	COSMIC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.2778
p.P1783S	TCGA-VS-A958	CESC	TCGA	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.1389
p.P1783L	TCGA-WE-AAA0	SKCM	TCGA	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.1389
p.P1758S	TCGA-YG-AA3N	SKCM	TCGA	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.1389
p.A1761V	DO51878	BLCA	ICGC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.2222
p.A1761V	DO223286	UCEC	ICGC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.2222
p.E1779K	DO219064	BLCA	ICGC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.25
p.E1779K	ACH-002509	Skin Cancer	CCLE	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.25
p.T173K	DO225012	BRCA	ICGC	LTPVGT	DEG_SCF_FBW7_1	159:164	Mutation rewiring degron network	0.0833
p.P1778S	DO51639	CESC	ICGC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.2778
p.K1772N	DO8882	COAD	ICGC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation altering degron motif	0.6918
p.T160A	DO8264	COAD	ICGC	LTPVGT	DEG_SCF_FBW7_1	159:164	Mutation altering degron motif	0.7139
p.V156A	DO230311	COCA	ICGC	LTPVGT	DEG_SCF_FBW7_1	159:164	Mutation rewiring degron network	0.25
p.K1766N	DO222798	COCA	ICGC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation altering degron motif	0.6918
p.K1766N	DO42400	UCEC	ICGC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation altering degron motif	0.6918
p.K1766N	ACH-000993	Endometrial/Uterine Cancer	CCLE	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation altering degron motif	0.6918
p.P1757H	DO234216	ESAD	ICGC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.1111
p.K1771R	DO234325	ESAD	ICGC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation altering degron motif	0.7237
p.K1771T	DO234373	ESAD	ICGC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation altering degron motif	0.7306
p.K1771N	DO234377	ESAD	ICGC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation altering degron motif	0.6918
p.K1771N	DO41542	UCEC	ICGC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation altering degron motif	0.6918
p.K1771N	SIDM01588	Endometrial Carcinoma	GDSC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation altering degron motif	0.6918
p.I171T	DO233762	GACA	ICGC	LTPVGT	DEG_SCF_FBW7_1	159:164	Mutation rewiring degron network	0.1389
p.G1775E	DO233830	GACA	ICGC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation altering degron motif	0.7199
p.G1775E	DO229459	SKCA	ICGC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation altering degron motif	0.7199
p.H154N	DO229029	LICA	ICGC	LTPVGT	DEG_SCF_FBW7_1	159:164	Mutation rewiring degron network	0.1944
p.S1765C	DO22812	LICA	ICGC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation altering degron motif	0.7541
p.A1758P	DO23428	LINC	ICGC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.1389
p.P1762L	DO25659	LUAD	ICGC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.25
p.P1762L	SW684	soft tissue	COSMIC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.25
p.T151S	DO25416	LUAD	ICGC	LTPVGT	DEG_SCF_FBW7_1	159:164	Mutation rewiring degron network	0.1111
p.P1774Q	DO24692	LUAD	ICGC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation altering degron motif	0.7035
p.G168C	DO224566	LUSC	ICGC	LTPVGT	DEG_SCF_FBW7_1	159:164	Mutation rewiring degron network	0.2222
p.G168C	DO231007	LUSC	ICGC	LTPVGT	DEG_SCF_FBW7_1	159:164	Mutation rewiring degron network	0.2222
p.G168V	DO224566	LUSC	ICGC	LTPVGT	DEG_SCF_FBW7_1	159:164	Mutation rewiring degron network	0.2222
p.G168V	DO231007	LUSC	ICGC	LTPVGT	DEG_SCF_FBW7_1	159:164	Mutation rewiring degron network	0.2222
p.P1759T	DO26830	LUSC	ICGC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.1667
p.T160I	DO50104	LUSC	ICGC	LTPVGT	DEG_SCF_FBW7_1	159:164	Mutation altering degron motif	0.7078
p.N1782K	DO50095	LUSC	ICGC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.1667
p.C1771Y	DO26794	LUSC	ICGC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation altering degron motif	0.7087
p.A1758D	DO219219	LUSC	ICGC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.1389
p.P166T	DO27200	LUSC	ICGC	LTPVGT	DEG_SCF_FBW7_1	159:164	Mutation rewiring degron network	0.2778
p.T1781N	DO27136	LUSC	ICGC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.1944
p.L1767M	DO52686	MALY	ICGC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation altering degron motif	0.711
p.L1785H	DO222504	MELA	ICGC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.0833
p.P1765S	DO222532	MELA	ICGC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation altering degron motif	0.6752
p.S1773L	DO222710	MELA	ICGC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation altering degron motif	0.7667
p.S1773L	DO47619	SKCM	ICGC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation altering degron motif	0.7667
p.S1773L	DO51259	SKCM	ICGC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation altering degron motif	0.7667
p.G174E	DO222843	MELA	ICGC	LTPVGT	DEG_SCF_FBW7_1	159:164	Mutation rewiring degron network	0.0556
p.G174E	DO50287	SKCM	ICGC	LTPVGT	DEG_SCF_FBW7_1	159:164	Mutation rewiring degron network	0.0556
p.G174E	DO51276	SKCM	ICGC	LTPVGT	DEG_SCF_FBW7_1	159:164	Mutation rewiring degron network	0.0556
p.P1756L	DO229162	NKTL	ICGC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.0833
p.T1783R	DO28068	OV	ICGC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.1389
p.S1779Y	DO36881	READ	ICGC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.25
p.P150H	DO37643	SKCM	ICGC	LTPVGT	DEG_SCF_FBW7_1	159:164	Mutation rewiring degron network	0.0833
p.P150H	DO37405	SKCM	ICGC	LTPVGT	DEG_SCF_FBW7_1	159:164	Mutation rewiring degron network	0.0833
p.P1770S	DO50287	SKCM	ICGC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation altering degron motif	0.6752
p.G174R	DO223908	SKCM	ICGC	LTPVGT	DEG_SCF_FBW7_1	159:164	Mutation rewiring degron network	0.0556
p.P1776L	DO229234	THCA	ICGC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation altering degron motif	0.7582
p.P1776L	ETK-1	biliary tract	COSMIC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation altering degron motif	0.7582
p.Y157H	DO42023	UCEC	ICGC	LTPVGT	DEG_SCF_FBW7_1	159:164	Mutation rewiring degron network	0.2778
p.P1780H	DO223286	UCEC	ICGC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.2222
p.R1764I	DO43041	UCEC	ICGC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.3056
p.G1776S	DO52402	UCEC	ICGC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation altering degron motif	0.6993
p.G1776S	DO43755	UCEC	ICGC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation altering degron motif	0.6993
p.T170I	DO42472	UCEC	ICGC	LTPVGT	DEG_SCF_FBW7_1	159:164	Mutation rewiring degron network	0.1667
p.G1756D	DO41488	UCEC	ICGC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.0833
p.A1773S	SIDM00984	Other Blood Cancers	GDSC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation altering degron motif	0.7588
p.A1773S	BONNA-12	haematopoietic and lymphoid tissue	COSMIC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation altering degron motif	0.7588
p.N162S	SIDM00277	Acute Myeloid Leukemia	GDSC	LTPVGT	DEG_SCF_FBW7_1	159:164	Mutation altering degron motif	0.7069
p.N162S	EoL-1-cell	haematopoietic and lymphoid tissue	COSMIC	LTPVGT	DEG_SCF_FBW7_1	159:164	Mutation altering degron motif	0.7069
p.Q1763R	SIDM00660	Colorectal Carcinoma	GDSC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.2778
p.Q1763R	LS-411N	large intestine	COSMIC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.2778
p.N157S	ACH-000198	Leukemia	CCLE	LTPVGT	DEG_SCF_FBW7_1	159:164	Mutation rewiring degron network	0.2778
p.N157S	EoL-1-cell	haematopoietic and lymphoid tissue	COSMIC	LTPVGT	DEG_SCF_FBW7_1	159:164	Mutation rewiring degron network	0.2778
p.Y1757C	ACH-000687	Lymphoma	CCLE	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.1111
p.A1765D	ACH-000780	Lung Cancer	CCLE	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation altering degron motif	0.7793
p.A1765D	NCI-H1105	lung	COSMIC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation altering degron motif	0.7793
p.S1782C	ACH-000888	Lung Cancer	CCLE	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.1667
p.S1782C	NCI-H1793	lung	COSMIC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.1667
p.A1768P	ACH-000912	Lung Cancer	CCLE	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation altering degron motif	0.7503
p.Q1758R	ACH-000985	Colon/Colorectal Cancer	CCLE	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.1389
p.F170C	ACH-000987	Skin Cancer	CCLE	LTPVGT	DEG_SCF_FBW7_1	159:164	Mutation rewiring degron network	0.1667
p.F170C	Mewo	skin	COSMIC	LTPVGT	DEG_SCF_FBW7_1	159:164	Mutation rewiring degron network	0.1667
p.L1767V	ACH-001402	Cervical Cancer	CCLE	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation altering degron motif	0.6765
p.L1767V	SW756	cervix	COSMIC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation altering degron motif	0.6765
p.A1768S	ACH-001452	Leukemia	CCLE	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation altering degron motif	0.7588
p.V1759E	ACH-001533	Lymphoma	CCLE	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.1667
p.V1759L	ACH-001533	Lymphoma	CCLE	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.1667
p.P1769S	ACH-001696	Head and Neck Cancer	CCLE	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation altering degron motif	0.5641
p.P1771L	ACH-001858	Bile Duct Cancer	CCLE	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation altering degron motif	0.7582
p.P1771L	ACH-002237	Bile Duct Cancer	CCLE	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation altering degron motif	0.7582
p.P1771L	ETK-1	biliary tract	COSMIC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation altering degron motif	0.7582
p.P1771L	SW684	soft tissue	COSMIC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation altering degron motif	0.7582
p.P1764L	ACH-002029	Head and Neck Cancer	CCLE	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.3056
p.P1764L	ACH-002309	Sarcoma	CCLE	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.3056
p.P1764L	SW684	soft tissue	COSMIC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.3056
p.P1756T	NCI-H1793	lung	COSMIC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.0833
p.S1768F	U-698-M	haematopoietic and lymphoid tissue	COSMIC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation altering degron motif	0.7982
p.A1786V	CCK-81	large intestine	COSMIC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.0556
p.P1766L	ETK-1	biliary tract	COSMIC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation altering degron motif	0.7582
p.P1778L	ETK-1	biliary tract	COSMIC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.2778
p.A1772S	BONNA-12	haematopoietic and lymphoid tissue	COSMIC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation altering degron motif	0.7588
p.S1779C	NCI-H1793	lung	COSMIC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.25
p.A1760D	NCI-H1105	lung	COSMIC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.1944
p.P1759L	SK-MEL-5	skin	COSMIC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.1667
p.P1759L	SW684	soft tissue	COSMIC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.1667
p.P1786L	SK-MEL-5	skin	COSMIC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.0556
p.A1766S	BONNA-12	haematopoietic and lymphoid tissue	COSMIC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation altering degron motif	0.7588
p.T172K	HPAF-II	pancreas	COSMIC	LTPVGT	DEG_SCF_FBW7_1	159:164	Mutation rewiring degron network	0.1111
p.T172K	NCI-H1975	lung	COSMIC	LTPVGT	DEG_SCF_FBW7_1	159:164	Mutation rewiring degron network	0.1111
p.A1772D	NCI-H1105	lung	COSMIC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation altering degron motif	0.7793
p.S1784C	NCI-H1793	lung	COSMIC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.1111
p.A1770D	NCI-H1105	lung	COSMIC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation altering degron motif	0.7793
p.L1774V	SW756	cervix	COSMIC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation altering degron motif	0.6765
p.P1758T	NCI-H1793	lung	COSMIC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.1389
p.L1765V	SW756	cervix	COSMIC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation altering degron motif	0.6765
p.C1760F	NCI-H250	lung	COSMIC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.1944
p.L1772V	SW756	cervix	COSMIC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation altering degron motif	0.6765
p.P1757L	SK-MEL-5	skin	COSMIC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.1111
p.L1762V	SW756	cervix	COSMIC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.25
p.S1759C	NCI-H1793	lung	COSMIC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.1667
p.I165K	EN	endometrium	COSMIC	LTPVGT	DEG_SCF_FBW7_1	159:164	Mutation rewiring degron network	0.3056
p.S1770F	U-698-M	haematopoietic and lymphoid tissue	COSMIC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation altering degron motif	0.7982
p.Q1762R	LS-411N	large intestine	COSMIC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.25
p.P1769L	SW684	soft tissue	COSMIC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation altering degron motif	0.6471
p.P1769L	ETK-1	biliary tract	COSMIC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation altering degron motif	0.6471
p.Q1756R	LS-411N	large intestine	COSMIC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.0833
p.Y167N	HCC-366	lung	COSMIC	LTPVGT	DEG_SCF_FBW7_1	159:164	Mutation rewiring degron network	0.25
p.C1758F	NCI-H250	lung	COSMIC	LAPPPDISPFSL	DEG_ODPH_VHL_1	1765:1776	Mutation rewiring degron network	0.1389

DegronMD: protein-targeted degradation, mutation and drug response to degrons

PCDH15

UniProt ID: Q96QU1

Entrez ID: 65217

Protein name: Protocadherin-15

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for PCDH15 in