DegronMD - Q99848(EBNA1BP2)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E65Q	TCGA-63-A5MS	LUSC	TCGA	DVTLGPVPEI	DEG_COP1_1	71:80	Mutation rewiring degron network	0.1667
p.E65Q	DO219161	LUSC	ICGC	DVTLGPVPEI	DEG_COP1_1	71:80	Mutation rewiring degron network	0.1667
p.E67D	TCGA-AP-A1DV	UCEC	TCGA	DVTLGPVPEI	DEG_COP1_1	71:80	Mutation rewiring degron network	0.2222
p.E67D	DO43186	UCEC	ICGC	DVTLGPVPEI	DEG_COP1_1	71:80	Mutation rewiring degron network	0.2222
p.V8I	TCGA-AZ-4615	COAD	TCGA	MDTPPLS	DEG_SCF_FBW7_1	1:7	Mutation rewiring degron network	0.3056
p.V8I	DO7977	COAD	ICGC	MDTPPLS	DEG_SCF_FBW7_1	1:7	Mutation rewiring degron network	0.3056
p.D80G	TCGA-DD-A1EJ	LIHC	TCGA	DVTLGPVPEI	DEG_COP1_1	71:80	Mutation altering degron motif	0.7198
p.D80G	DO22994	LIHC	ICGC	DVTLGPVPEI	DEG_COP1_1	71:80	Mutation altering degron motif	0.7198
p.R76K	DO48428	BLCA	ICGC	DVTLGPVPEI	DEG_COP1_1	71:80	Mutation altering degron motif	0.7237
p.R76K	SIDM01690	Plasma Cell Myeloma	GDSC	DVTLGPVPEI	DEG_COP1_1	71:80	Mutation altering degron motif	0.7237
p.F17L	DO233781	GACA	ICGC	MDTPPLS	DEG_SCF_FBW7_1	1:7	Mutation rewiring degron network	0.0556
p.F17L	DO229038	LICA	ICGC	MDTPPLS	DEG_SCF_FBW7_1	1:7	Mutation rewiring degron network	0.0556
p.L86I	DO229031	LICA	ICGC	DVTLGPVPEI	DEG_COP1_1	71:80	Mutation rewiring degron network	0.1667
p.E67K	DO229050	LICA	ICGC	DVTLGPVPEI	DEG_COP1_1	71:80	Mutation rewiring degron network	0.2222
p.E4K	DO220899	MELA	ICGC	MDTPPLS	DEG_SCF_FBW7_1	1:7	Mutation altering degron motif	0.7022
p.V73A	SIDM00118	Colorectal Carcinoma	GDSC	DVTLGPVPEI	DEG_COP1_1	71:80	Mutation altering degron motif	0.6936
p.V73A	HCC2998	large intestine	COSMIC	DVTLGPVPEI	DEG_COP1_1	71:80	Mutation altering degron motif	0.6936
p.G81S	ACH-000953	Leukemia	CCLE	DVTLGPVPEI	DEG_COP1_1	71:80	Mutation rewiring degron network	0.3056
p.G81S	SUP-T1	haematopoietic and lymphoid tissue	COSMIC	DVTLGPVPEI	DEG_COP1_1	71:80	Mutation rewiring degron network	0.3056
p.V72A	ACH-000985	Colon/Colorectal Cancer	CCLE	DVTLGPVPEI	DEG_COP1_1	71:80	Mutation altering degron motif	0.5825
p.V72A	LS-411N	large intestine	COSMIC	DVTLGPVPEI	DEG_COP1_1	71:80	Mutation altering degron motif	0.5825
p.E68K	ACH-001138	Lung Cancer	CCLE	DVTLGPVPEI	DEG_COP1_1	71:80	Mutation rewiring degron network	0.25
p.E68K	NCI-H2141	lung	COSMIC	DVTLGPVPEI	DEG_COP1_1	71:80	Mutation rewiring degron network	0.25
p.G81V	ACH-002222	Leukemia	CCLE	DVTLGPVPEI	DEG_COP1_1	71:80	Mutation rewiring degron network	0.3056
p.G81V	CTV-1	haematopoietic and lymphoid tissue	COSMIC	DVTLGPVPEI	DEG_COP1_1	71:80	Mutation rewiring degron network	0.3056

Kaplan plot for EBNA1BP2 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

EBNA1BP2

UniProt ID: Q99848

Entrez ID: 10969

Protein name: Probable rRNA-processing protein EBP2 (EBNA1-binding protein 2) (Nucleolar protein p40)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for EBNA1BP2 in