DegronMD - Q9BYG3(NIFK)

NIFK

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.T227N	TCGA-AX-A2HD	UCEC	TCGA	LDTPEKT	DEG_SCF_FBW7_1	221:227	Mutation altering degron motif	0.8166
p.G232D	TCGA-BR-4184	STAD	TCGA	LDTPEKT	DEG_SCF_FBW7_1	221:227	Mutation rewiring degron network	0.1944
p.G232D	TCGA-BR-4184	STAD	TCGA	PTPVCT	DEG_SCF_FBW7_1	233:238	Mutation rewiring degron network	0.3056
p.S247C	SIDM00491	Thyroid Gland Carcinoma	GDSC	PTPVCT	DEG_SCF_FBW7_1	233:238	Mutation blocking phosphorylation signal	0.5278
p.S247C	ASH-3	thyroid	COSMIC	PTPVCT	DEG_SCF_FBW7_1	233:238	Mutation blocking phosphorylation signal	0.5278
p.T234S	SIDM00523	Small Cell Lung Carcinoma	GDSC	PTPVCT	DEG_SCF_FBW7_1	233:238	Mutation altering degron motif	0.8227
p.R245Q	SIDM01398	Melanoma	GDSC	PTPVCT	DEG_SCF_FBW7_1	233:238	Mutation rewiring degron network	0.1389

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*NOTE: the Kaplan plots were collected from OncoLnc