DegronMD - Q9H079(KATNBL1)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S92N	TCGA-90-7767	LUSC	TCGA	NKENE	DEG_APCC_KENBOX_2	99:103	Mutation rewiring degron network	0.1389
p.S92N	DO26692	LUSC	ICGC	NKENE	DEG_APCC_KENBOX_2	99:103	Mutation rewiring degron network	0.1389
p.R119Q	TCGA-AN-A046	BRCA	TCGA	DSGSSQT	DEG_SCF_TRCP1_1	127:133	Mutation rewiring degron network	0.1111
p.R119Q	DO1285	BRCA	ICGC	DSGSSQT	DEG_SCF_TRCP1_1	127:133	Mutation rewiring degron network	0.1111
p.R119Q	SIDM00118	Colorectal Carcinoma	GDSC	DSGSSQT	DEG_SCF_TRCP1_1	127:133	Mutation rewiring degron network	0.1111
p.R119Q	ACH-001081	Colon/Colorectal Cancer	CCLE	DSGSSQT	DEG_SCF_TRCP1_1	127:133	Mutation rewiring degron network	0.1111
p.R119Q	HCC2998	large intestine	COSMIC	DSGSSQT	DEG_SCF_TRCP1_1	127:133	Mutation rewiring degron network	0.1111
p.A105D	TCGA-AP-A059	UCEC	TCGA	NKENE	DEG_APCC_KENBOX_2	99:103	Mutation rewiring degron network	0.2778
p.A105D	DO41361	UCEC	ICGC	NKENE	DEG_APCC_KENBOX_2	99:103	Mutation rewiring degron network	0.2778
p.A107T	TCGA-AP-A1DM	UCEC	TCGA	NKENE	DEG_APCC_KENBOX_2	99:103	Mutation rewiring degron network	0.2222
p.A107T	DO43106	UCEC	ICGC	NKENE	DEG_APCC_KENBOX_2	99:103	Mutation rewiring degron network	0.2222
p.T120A	TCGA-CG-5723	STAD	TCGA	DSGSSQT	DEG_SCF_TRCP1_1	127:133	Mutation rewiring degron network	0.1389
p.T120A	DO38376	STAD	ICGC	DSGSSQT	DEG_SCF_TRCP1_1	127:133	Mutation rewiring degron network	0.1389
p.D127N	TCGA-EE-A29L	SKCM	TCGA	DSGSSQT	DEG_SCF_TRCP1_1	127:133	Mutation altering degron motif	0.6932
p.D127N	DO222599	MELA	ICGC	DSGSSQT	DEG_SCF_TRCP1_1	127:133	Mutation altering degron motif	0.6932
p.D127N	DO37835	SKCM	ICGC	DSGSSQT	DEG_SCF_TRCP1_1	127:133	Mutation altering degron motif	0.6932
p.A98E	DO228952	LICA	ICGC	NKENE	DEG_APCC_KENBOX_2	99:103	Mutation rewiring degron network	0.3056
p.H109N	DO229019	LICA	ICGC	NKENE	DEG_APCC_KENBOX_2	99:103	Mutation rewiring degron network	0.1667
p.P111T	DO229024	LICA	ICGC	NKENE	DEG_APCC_KENBOX_2	99:103	Mutation rewiring degron network	0.1111
p.H109R	SIDM00683	Prostate Carcinoma	GDSC	NKENE	DEG_APCC_KENBOX_2	99:103	Mutation rewiring degron network	0.1667
p.H109R	ACH-000977	lymph node	CCLE	NKENE	DEG_APCC_KENBOX_2	99:103	Mutation rewiring degron network	0.1667
p.H109R	LNCaP-Clone-FGC	prostate	COSMIC	NKENE	DEG_APCC_KENBOX_2	99:103	Mutation rewiring degron network	0.1667
p.D96Y	SIDM00138	Non-Small Cell Lung Carcinoma	GDSC	NKENE	DEG_APCC_KENBOX_2	99:103	Mutation rewiring degron network	0.25
p.D96Y	ACH-000900	Lung Cancer	CCLE	NKENE	DEG_APCC_KENBOX_2	99:103	Mutation rewiring degron network	0.25
p.D96Y	NCI-H23	lung	COSMIC	NKENE	DEG_APCC_KENBOX_2	99:103	Mutation rewiring degron network	0.25

Kaplan plot for KATNBL1 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

KATNBL1

UniProt ID: Q9H079

Entrez ID: 79768

Protein name: KATNB1-like protein 1 (Katanin p80 subunit B-like 1)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for KATNBL1 in