DegronMD - Q9P203(BTBD7)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A741P	TCGA-34-2604	LUSC	TCGA	VNSTPPAE	DEG_SCF_FBW7_2	735:742	Mutation altering degron motif	0.6392
p.A741P	DO26433	LUSC	ICGC	VNSTPPAE	DEG_SCF_FBW7_2	735:742	Mutation altering degron motif	0.6392
p.T964P	TCGA-38-4632	LUAD	TCGA	PSTPALS	DEG_SCF_FBW7_1	955:961	Mutation blocking phosphorylation signal	0.6944
p.T964P	DO23858	LUAD	ICGC	PSTPALS	DEG_SCF_FBW7_1	955:961	Mutation blocking phosphorylation signal	0.6944
p.V735L	TCGA-64-1679	LUAD	TCGA	VNSTPPAE	DEG_SCF_FBW7_2	735:742	Mutation altering degron motif	0.5654
p.V735L	DO26200	LUAD	ICGC	VNSTPPAE	DEG_SCF_FBW7_2	735:742	Mutation altering degron motif	0.5654
p.G731E	TCGA-D3-A1Q8	SKCM	TCGA	VNSTPPAE	DEG_SCF_FBW7_2	735:742	Mutation rewiring degron network	0.2222
p.G731E	DO37446	SKCM	ICGC	VNSTPPAE	DEG_SCF_FBW7_2	735:742	Mutation rewiring degron network	0.2222
p.P967S	TCGA-D3-A3C8	SKCM	TCGA	PSTPALS	DEG_SCF_FBW7_1	955:961	Mutation rewiring degron network	0.1667
p.P967S	DO47636	SKCM	ICGC	PSTPALS	DEG_SCF_FBW7_1	955:961	Mutation rewiring degron network	0.1667
p.V735A	TCGA-F7-A624	HNSC	TCGA	VNSTPPAE	DEG_SCF_FBW7_2	735:742	Mutation altering degron motif	0.6936
p.V735A	DO44440	HNSC	ICGC	VNSTPPAE	DEG_SCF_FBW7_2	735:742	Mutation altering degron motif	0.6936
p.Q969H	TCGA-MP-A4TD	LUAD	TCGA	PSTPALS	DEG_SCF_FBW7_1	955:961	Mutation rewiring degron network	0.1111
p.Q969H	DO45363	LUAD	ICGC	PSTPALS	DEG_SCF_FBW7_1	955:961	Mutation rewiring degron network	0.1111
p.F945L	DO233652	GACA	ICGC	PSTPALS	DEG_SCF_FBW7_1	955:961	Mutation rewiring degron network	0.0556
p.H766Y	DO229177	LMS	ICGC	PPPY	ITCH	762:765	Mutation rewiring degron network	0.3056
p.P756L	DO220877	MELA	ICGC	PPPY	ITCH	762:765	Mutation rewiring degron network	0.1667
p.P967L	ACH-001563	Skin Cancer	CCLE	PSTPALS	DEG_SCF_FBW7_1	955:961	Mutation rewiring degron network	0.1667

Kaplan plot for BTBD7 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

BTBD7

UniProt ID: Q9P203

Entrez ID: 55727

Protein name: BTB/POZ domain-containing protein 7

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for BTBD7 in