DegronMD - Q9UHR5(SAP30BP)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G226C	TCGA-05-4384	LUAD	TCGA	ATSTT	DEG_SPOP_SBC_1	235:239	Mutation rewiring degron network	0.0833
p.E21Q	TCGA-05-4424	LUAD	TCGA	LAVYAE	LIG_APCC_ABBA_1	11:16	Mutation rewiring degron network	0.1944
p.E21Q	DO23672	LUAD	ICGC	LAVYAE	LIG_APCC_ABBA_1	11:16	Mutation rewiring degron network	0.1944
p.E25Q	TCGA-49-6745	LUAD	TCGA	LAVYAE	LIG_APCC_ABBA_1	11:16	Mutation rewiring degron network	0.0833
p.E25Q	DO23862	LUAD	ICGC	LAVYAE	LIG_APCC_ABBA_1	11:16	Mutation rewiring degron network	0.0833
p.A243T	TCGA-AB-2807	LAML	TCGA	ATSTT	DEG_SPOP_SBC_1	235:239	Mutation rewiring degron network	0.2222
p.A248V	TCGA-AP-A1DK	UCEC	TCGA	ATSTT	DEG_SPOP_SBC_1	235:239	Mutation rewiring degron network	0.0833
p.G230A	TCGA-AT-A5NU	KIRP	TCGA	ATSTT	DEG_SPOP_SBC_1	235:239	Mutation rewiring degron network	0.1944
p.G3W	TCGA-BF-A1Q0	SKCM	TCGA	LAVYAE	LIG_APCC_ABBA_1	11:16	Mutation rewiring degron network	0.1111
p.G3W	DO47374	SKCM	ICGC	LAVYAE	LIG_APCC_ABBA_1	11:16	Mutation rewiring degron network	0.1111
p.L11F	DO222650	BTCA	ICGC	LAVYAE	LIG_APCC_ABBA_1	11:16	Mutation altering degron motif	0.587
p.A227T	DO21589	LAML	ICGC	ATSTT	DEG_SPOP_SBC_1	235:239	Mutation rewiring degron network	0.1111
p.R237K	DO220873	MELA	ICGC	ATSTT	DEG_SPOP_SBC_1	235:239	Mutation altering degron motif	0.7237
p.T238I	DO229470	SKCA	ICGC	ATSTT	DEG_SPOP_SBC_1	235:239	Mutation altering degron motif	0.7078
p.A232V	DO42033	UCEC	ICGC	ATSTT	DEG_SPOP_SBC_1	235:239	Mutation rewiring degron network	0.25
p.S243L	DO41331	UCEC	ICGC	ATSTT	DEG_SPOP_SBC_1	235:239	Mutation rewiring degron network	0.2222
p.G3R	SIDM00789	Colorectal Carcinoma	GDSC	LAVYAE	LIG_APCC_ABBA_1	11:16	Mutation rewiring degron network	0.1111
p.G3R	ACH-000997	Colon/Colorectal Cancer	CCLE	LAVYAE	LIG_APCC_ABBA_1	11:16	Mutation rewiring degron network	0.1111
p.G3R	ACH-001061	Colon/Colorectal Cancer	CCLE	LAVYAE	LIG_APCC_ABBA_1	11:16	Mutation rewiring degron network	0.1111
p.G3R	HCT-15	large intestine	COSMIC	LAVYAE	LIG_APCC_ABBA_1	11:16	Mutation rewiring degron network	0.1111

Kaplan plot for SAP30BP in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

SAP30BP

UniProt ID: Q9UHR5

Entrez ID: 29115

Protein name: SAP30-binding protein (Transcriptional regulator protein HCNGP)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for SAP30BP in