DegronMD - Q9ULG6(CCPG1)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A39T	TCGA-77-7337	LUSC	TCGA	VTPTDS	DEG_SCF_FBW7_1	30:35	Mutation rewiring degron network	0.2222
p.A39T	DO27445	LUSC	ICGC	VTPTDS	DEG_SCF_FBW7_1	30:35	Mutation rewiring degron network	0.2222
p.A39T	SIDM00680	Colorectal Carcinoma	GDSC	VTPTDS	DEG_SCF_FBW7_1	30:35	Mutation rewiring degron network	0.2222
p.A39T	LS-180	large intestine	COSMIC	VTPTDS	DEG_SCF_FBW7_1	30:35	Mutation rewiring degron network	0.2222
p.S35N	TCGA-A5-A0G1	UCEC	TCGA	VTPTDS	DEG_SCF_FBW7_1	30:35	Mutation altering degron motif	0.7069
p.S35N	DO42472	UCEC	ICGC	VTPTDS	DEG_SCF_FBW7_1	30:35	Mutation altering degron motif	0.7069
p.E399G	TCGA-BS-A0UV	UCEC	TCGA	LRGELQQLS	DEG_APCC_DBOX_1	396:404	Mutation altering degron motif	0.6087
p.E399G	DO42793	UCEC	ICGC	LRGELQQLS	DEG_APCC_DBOX_1	396:404	Mutation altering degron motif	0.6087
p.E41K	TCGA-C5-A7CL	CESC	TCGA	VTPTDS	DEG_SCF_FBW7_1	30:35	Mutation rewiring degron network	0.1667
p.E41K	DO49887	CESC	ICGC	VTPTDS	DEG_SCF_FBW7_1	30:35	Mutation rewiring degron network	0.1667
p.A395S	TCGA-DS-A0VM	CESC	TCGA	LRGELQQLS	DEG_APCC_DBOX_1	396:404	Mutation rewiring degron network	0.3056
p.A395S	DO6258	CESC	ICGC	LRGELQQLS	DEG_APCC_DBOX_1	396:404	Mutation rewiring degron network	0.3056
p.T31S	TCGA-E9-A24A	BRCA	TCGA	VTPTDS	DEG_SCF_FBW7_1	30:35	Mutation altering degron motif	0.7116
p.T31S	DO4861	BRCA	ICGC	VTPTDS	DEG_SCF_FBW7_1	30:35	Mutation altering degron motif	0.7116
p.G21W	TCGA-GN-A26C	SKCM	TCGA	VTPTDS	DEG_SCF_FBW7_1	30:35	Mutation rewiring degron network	0.0833
p.G21W	DO37782	SKCM	ICGC	VTPTDS	DEG_SCF_FBW7_1	30:35	Mutation rewiring degron network	0.0833
p.S35C	TCGA-MN-A4N4	LUAD	TCGA	VTPTDS	DEG_SCF_FBW7_1	30:35	Mutation altering degron motif	0.7541
p.S35C	DO26250	LUAD	ICGC	VTPTDS	DEG_SCF_FBW7_1	30:35	Mutation altering degron motif	0.7541
p.A395D	DO228952	LICA	ICGC	LRGELQQLS	DEG_APCC_DBOX_1	396:404	Mutation rewiring degron network	0.3056
p.R397S	SIDM00390	T-Cell Non-Hodgkin's Lymphoma	GDSC	LRGELQQLS	DEG_APCC_DBOX_1	396:404	Mutation altering degron motif	0.7427
p.R397S	ACH-000664	Lymphoma	CCLE	LRGELQQLS	DEG_APCC_DBOX_1	396:404	Mutation altering degron motif	0.7427
p.R397S	SU-DHL-1	haematopoietic and lymphoid tissue	COSMIC	LRGELQQLS	DEG_APCC_DBOX_1	396:404	Mutation altering degron motif	0.7427
p.G398V	SIDM00789	Colorectal Carcinoma	GDSC	LRGELQQLS	DEG_APCC_DBOX_1	396:404	Mutation altering degron motif	0.6421
p.G398V	ACH-000997	Colon/Colorectal Cancer	CCLE	LRGELQQLS	DEG_APCC_DBOX_1	396:404	Mutation altering degron motif	0.6421
p.G398V	ACH-001061	Colon/Colorectal Cancer	CCLE	LRGELQQLS	DEG_APCC_DBOX_1	396:404	Mutation altering degron motif	0.6421
p.G398V	HCT-15	large intestine	COSMIC	LRGELQQLS	DEG_APCC_DBOX_1	396:404	Mutation altering degron motif	0.6421
p.H409R	SIDM00043	Head and Neck Carcinoma	GDSC	LRGELQQLS	DEG_APCC_DBOX_1	396:404	Mutation rewiring degron network	0.1944
p.H409R	ACH-002297	Head and Neck Cancer	CCLE	LRGELQQLS	DEG_APCC_DBOX_1	396:404	Mutation rewiring degron network	0.1944
p.H409R	PCI-4B	upper aerodigestive tract	COSMIC	LRGELQQLS	DEG_APCC_DBOX_1	396:404	Mutation rewiring degron network	0.1944
p.M26K	SIDM01619	Endometrial Carcinoma	GDSC	VTPTDS	DEG_SCF_FBW7_1	30:35	Mutation rewiring degron network	0.2222
p.M26K	ACH-000984	Endometrial/Uterine Cancer	CCLE	VTPTDS	DEG_SCF_FBW7_1	30:35	Mutation rewiring degron network	0.2222
p.S22P	ACH-000999	Colon/Colorectal Cancer	CCLE	VTPTDS	DEG_SCF_FBW7_1	30:35	Mutation rewiring degron network	0.1111
p.S22P	SNU-1040	large intestine	COSMIC	VTPTDS	DEG_SCF_FBW7_1	30:35	Mutation rewiring degron network	0.1111

Kaplan plot for CCPG1 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

CCPG1

UniProt ID: Q9ULG6

Entrez ID: 9236

Protein name: Cell cycle progression protein 1 (Cell cycle progression restoration protein 8)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for CCPG1 in