DegronMD - Q9Y242(TCF19)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G11W	TCGA-A5-A1OF	UCEC	TCGA	DLYTFHP	CBL_PTK	17:23	Mutation rewiring degron network	0.1667
p.G11W	DO42568	UCEC	ICGC	DLYTFHP	CBL_PTK	17:23	Mutation rewiring degron network	0.1667
p.R9H	TCGA-BR-8360	STAD	TCGA	DLYTFHP	CBL_PTK	17:23	Mutation blocking phosphorylation signal	0.5556
p.R9H	DO47745	STAD	ICGC	DLYTFHP	CBL_PTK	17:23	Mutation blocking phosphorylation signal	0.5556
p.E49D	TCGA-EJ-5503	PRAD	TCGA	HRADLCDVA	DEG_APCC_DBOX_1	35:43	Mutation rewiring degron network	0.1667
p.E49D	DO36359	PRAD	ICGC	HRADLCDVA	DEG_APCC_DBOX_1	35:43	Mutation rewiring degron network	0.1667
p.A43S	TCGA-FS-A1Z4	SKCM	TCGA	HRADLCDVA	DEG_APCC_DBOX_1	35:43	Mutation altering degron motif	0.6477
p.A43S	DO37462	SKCM	ICGC	HRADLCDVA	DEG_APCC_DBOX_1	35:43	Mutation altering degron motif	0.6477
p.G34C	DO225361	BRCA	ICGC	HRADLCDVA	DEG_APCC_DBOX_1	35:43	Mutation rewiring degron network	0.3056
p.H22P	DO219881	SKCA	ICGC	DLYTFHP	CBL_PTK	17:23	Mutation altering degron motif	0.6583
p.R45W	DO229213	THCA	ICGC	HRADLCDVA	DEG_APCC_DBOX_1	35:43	Mutation rewiring degron network	0.2778
p.G26R	SIDM00794	Other Solid Cancers	GDSC	HRADLCDVA	DEG_APCC_DBOX_1	35:43	Mutation rewiring degron network	0.0833
p.G26R	SIDM00794	Other Solid Cancers	GDSC	DLYTFHP	CBL_PTK	17:23	Mutation rewiring degron network	0.25
p.G13D	ACH-000979	Prostate Cancer	CCLE	DLYTFHP	CBL_PTK	17:23	Mutation rewiring degron network	0.2222
p.R32H	ACH-001377	Pancreatic Cancer	CCLE	HRADLCDVA	DEG_APCC_DBOX_1	35:43	Mutation rewiring degron network	0.25
p.R32H	ACH-001377	Pancreatic Cancer	CCLE	DLYTFHP	CBL_PTK	17:23	Mutation rewiring degron network	0.0833

Kaplan plot for TCF19 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

TCF19

UniProt ID: Q9Y242

Entrez ID: 6941

Protein name: Transcription factor 19 (TCF-19) (Transcription factor SC1)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for TCF19 in