DegronMD - Q9Y334(VWA7)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Data table is loading....

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S419F	TCGA-63-A5MB	LUSC	TCGA	IFVFTD	LIG_APCC_ABBA_1	412:417	Mutation rewiring degron network	0.2778
p.S419F	DO52018	LUSC	ICGC	IFVFTD	LIG_APCC_ABBA_1	412:417	Mutation rewiring degron network	0.2778
p.P351H	TCGA-AX-A1CE	UCEC	TCGA	LVPFHD	LIG_APCC_ABBA_1	356:361	Mutation rewiring degron network	0.1944
p.P351H	DO42280	UCEC	ICGC	LVPFHD	LIG_APCC_ABBA_1	356:361	Mutation rewiring degron network	0.1944
p.T426N	TCGA-BA-A6DJ	HNSC	TCGA	IFVFTD	LIG_APCC_ABBA_1	412:417	Mutation rewiring degron network	0.0833
p.T426N	DO52034	HNSC	ICGC	IFVFTD	LIG_APCC_ABBA_1	412:417	Mutation rewiring degron network	0.0833
p.P348S	TCGA-EE-A2MR	SKCM	TCGA	LVPFHD	LIG_APCC_ABBA_1	356:361	Mutation rewiring degron network	0.1111
p.P348S	DO37819	SKCM	ICGC	LVPFHD	LIG_APCC_ABBA_1	356:361	Mutation rewiring degron network	0.1111
p.L404P	TCGA-G4-6588	COAD	TCGA	IFVFTD	LIG_APCC_ABBA_1	412:417	Mutation rewiring degron network	0.1111
p.L404P	DO10140	COAD	ICGC	IFVFTD	LIG_APCC_ABBA_1	412:417	Mutation rewiring degron network	0.1111
p.P407H	TCGA-VQ-A8PX	STAD	TCGA	IFVFTD	LIG_APCC_ABBA_1	412:417	Mutation rewiring degron network	0.1944
p.P407H	DO51778	STAD	ICGC	IFVFTD	LIG_APCC_ABBA_1	412:417	Mutation rewiring degron network	0.1944
p.D411H	DO228483	BRCA	ICGC	IFVFTD	LIG_APCC_ABBA_1	412:417	Mutation rewiring degron network	0.3056
p.P351T	DO233103	GACA	ICGC	LVPFHD	LIG_APCC_ABBA_1	356:361	Mutation rewiring degron network	0.1944
p.S347N	DO233634	GACA	ICGC	LVPFHD	LIG_APCC_ABBA_1	356:361	Mutation rewiring degron network	0.0833
p.S347N	SIDM01619	Endometrial Carcinoma	GDSC	LVPFHD	LIG_APCC_ABBA_1	356:361	Mutation rewiring degron network	0.0833
p.S347N	ACH-000984	Endometrial/Uterine Cancer	CCLE	LVPFHD	LIG_APCC_ABBA_1	356:361	Mutation rewiring degron network	0.0833
p.T416M	DO233731	GACA	ICGC	IFVFTD	LIG_APCC_ABBA_1	412:417	Mutation altering degron motif	0.6312

Kaplan plot for VWA7 in

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

VWA7

UniProt ID: Q9Y334

Entrez ID: 80737

Protein name: von Willebrand factor A domain-containing protein 7 (Protein G7c)

External links: UniprotKB HGNC RefSeq COSMIC

Data table is loading....

Kaplan plot for VWA7 in