DegronMD - Q9Y462(ZNF711)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P13A	TCGA-60-2711	LUSC	TCGA	DSGGGS	DEG_SCF_TRCP1_1	2:7	Mutation rewiring degron network	0.1667
p.P13A	DO26987	LUSC	ICGC	DSGGGS	DEG_SCF_TRCP1_1	2:7	Mutation rewiring degron network	0.1667
p.K197N	TCGA-AP-A0LM	UCEC	TCGA	VKSTS	DEG_SPOP_SBC_1	196:200	Mutation altering degron motif	0.5806
p.K197N	DO43306	UCEC	ICGC	VKSTS	DEG_SPOP_SBC_1	196:200	Mutation altering degron motif	0.5806
p.T188A	TCGA-BR-4362	STAD	TCGA	VKSTS	DEG_SPOP_SBC_1	196:200	Mutation rewiring degron network	0.1111
p.T188A	DO38336	STAD	ICGC	VKSTS	DEG_SPOP_SBC_1	196:200	Mutation rewiring degron network	0.1111
p.D190E	TCGA-BR-8078	STAD	TCGA	VKSTS	DEG_SPOP_SBC_1	196:200	Mutation rewiring degron network	0.1667
p.D190E	DO38288	STAD	ICGC	VKSTS	DEG_SPOP_SBC_1	196:200	Mutation rewiring degron network	0.1667
p.R16I	TCGA-CN-4741	HNSC	TCGA	DSGGGS	DEG_SCF_TRCP1_1	2:7	Mutation rewiring degron network	0.0833
p.R16I	DO14313	HNSC	ICGC	DSGGGS	DEG_SCF_TRCP1_1	2:7	Mutation rewiring degron network	0.0833
p.D2N	TCGA-D3-A51T	SKCM	TCGA	DSGGGS	DEG_SCF_TRCP1_1	2:7	Mutation altering degron motif	0.6932
p.D2N	DO47389	SKCM	ICGC	DSGGGS	DEG_SCF_TRCP1_1	2:7	Mutation altering degron motif	0.6932
p.G5V	TCGA-DS-A5RQ	CESC	TCGA	DSGGGS	DEG_SCF_TRCP1_1	2:7	Mutation altering degron motif	0.6421
p.G5V	DO44392	CESC	ICGC	DSGGGS	DEG_SCF_TRCP1_1	2:7	Mutation altering degron motif	0.6421
p.R16T	TCGA-J1-A4AH	LUSC	TCGA	DSGGGS	DEG_SCF_TRCP1_1	2:7	Mutation rewiring degron network	0.0833
p.R16T	DO45479	LUSC	ICGC	DSGGGS	DEG_SCF_TRCP1_1	2:7	Mutation rewiring degron network	0.0833
p.D191N	TCGA-UY-A78O	BLCA	TCGA	VKSTS	DEG_SPOP_SBC_1	196:200	Mutation rewiring degron network	0.1944
p.D191N	DO219035	BLCA	ICGC	VKSTS	DEG_SPOP_SBC_1	196:200	Mutation rewiring degron network	0.1944
p.I186T	TCGA-XF-AAMQ	BLCA	TCGA	VKSTS	DEG_SPOP_SBC_1	196:200	Mutation rewiring degron network	0.0556
p.I186T	DO51934	BLCA	ICGC	VKSTS	DEG_SPOP_SBC_1	196:200	Mutation rewiring degron network	0.0556
p.M17V	DO228542	GACA	ICGC	DSGGGS	DEG_SCF_TRCP1_1	2:7	Mutation rewiring degron network	0.0556
p.G5C	DO229027	LICA	ICGC	DSGGGS	DEG_SCF_TRCP1_1	2:7	Mutation altering degron motif	0.6489
p.D194V	DO50820	LIRI	ICGC	VKSTS	DEG_SPOP_SBC_1	196:200	Mutation rewiring degron network	0.2778
p.K197R	DO228603	PRAD	ICGC	VKSTS	DEG_SPOP_SBC_1	196:200	Mutation altering degron motif	0.6126
p.I206M	SIDM00632	Non-Cancerous	GDSC	VKSTS	DEG_SPOP_SBC_1	196:200	Mutation rewiring degron network	0.1667
p.I206M	ACH-002247	Non-Cancerous	CCLE	VKSTS	DEG_SPOP_SBC_1	196:200	Mutation rewiring degron network	0.1667
p.I206M	IM-9	haematopoietic and lymphoid tissue	COSMIC	VKSTS	DEG_SPOP_SBC_1	196:200	Mutation rewiring degron network	0.1667
p.G6V	ACH-000681	Lung Cancer	CCLE	DSGGGS	DEG_SCF_TRCP1_1	2:7	Mutation altering degron motif	0.6421

Kaplan plot for ZNF711 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

ZNF711

UniProt ID: Q9Y462

Entrez ID: 7552

Protein name: Zinc finger protein 711 (Zinc finger protein 6)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for ZNF711 in