Personalized clinical immunopeptidomic sample cohorts analysis


The ImmuneApp 1.0 is also a semi-automated online tool that enables rapid assessment and analysis of single or multiple MHC class I immunopeptidomic datasets, including datasets generated from large clinical sample cohorts. Users can upload multiple immunopeptidomic datasets, and then select alleles annotated by the HLA typing tool. ImmuneApp 1.0 will return multi-level analysis results, including:

  • Quality control
  • Binding map visualization
  • Motif discovery (unsupervised and supervised)
  • Motif decomposition
  • HLA assignment
  • Antigen presentation prediction

Important note: Each job may take 10-30 minutes to finish. You may retrive the results anytime using the Job Identifier (JID e.g., JOB1234_1234567890). Please do keep a record of the JID.

To load data, copy-and-paste data into the text box OR select the sample files to upload.(You may load up to 8 samples for one job). Before clicking the "Run" button for analysis, please click the "Upload data" button.

Example result: A quick example result page can be checked here


Inputs


    Check HLA allele (n = 0; clear all)



    Loaded data:

    Sample name Description (optional) Alleles