CDC7
Entrez ID: 8317
Full name: cell division cycle 7
External links: HGNC UniprotKB Ensembl RefSeq COSMIC
Family: Other: CDC7
Chromosomal location: 1p22.1
Substructure location: Gatekeeper: 134 A-loop: 195...205, 366...378 G-loop: [N/A] αC-helix: 98...110
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CDC7
Seems to phosphorylate critical substrates that regulate the G1/S phase transition and/or DNA replication. Can phosphorylates MCM2 and MCM3....
Seems to phosphorylate critical substrates that regulate the G1/S phase transition and/or DNA replication. Can phosphorylates MCM2 and MCM3.
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GO - Biological processes (BP):
cell cycle phase transition, cell division, DNA replication, double-strand break repair via break-induced replication, G1/S transition of mitotic cell cycle, negative regulation of G0 to G1 transition, peptidyl-serine phosphorylation, positive regulation of cell population proliferation, positive re...
cell cycle phase transition, cell division, DNA replication, double-strand break repair via break-induced replication, G1/S transition of mitotic cell cycle, negative regulation of G0 to G1 transition, peptidyl-serine phosphorylation, positive regulation of cell population proliferation, positive regulation of G2/M transition of mitotic cell cycle, positive regulation of nuclear cell cycle DNA replication
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GO - Molecular function (MF):
ATP binding, kinase activity, metal ion binding, protein kinase activity, protein serine/threonine kinase activity...
ATP binding, kinase activity, metal ion binding, protein kinase activity, protein serine/threonine kinase activity
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GO - Cellular component (CC):
mitotic spindle, intercellular bridge, nucleoplasm, nucleus, cytoplasm...
mitotic spindle, intercellular bridge, nucleoplasm, nucleus, cytoplasm
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cell division cycle 7
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Kaplan plot for CDC7 in
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*NOTE: the Kaplan plots were collected from OncoLnc