TRIM66
Entrez ID: 9866
Full name: tripartite motif containing 66
External links: HGNC UniprotKB Ensembl RefSeq COSMIC
Family: Atypical: TIF1
Chromosomal location: 11p15.4
Substructure location: Gatekeeper: A-loop: G-loop: αC-helix:
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TRIM66
May function as transcription repressor; The repressive effects are mediated, at least in part, by recruitment of deacetylase activity. May play a role as negative regulator of postmeiotic genes acting through CBX3 complex formation and centromere association (By similarity)....
May function as transcription repressor; The repressive effects are mediated, at least in part, by recruitment of deacetylase activity. May play a role as negative regulator of postmeiotic genes acting through CBX3 complex formation and centromere association (By similarity).
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GO - Biological processes (BP):
negative regulation of transcription, DNA-templated...
negative regulation of transcription, DNA-templated
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GO - Molecular function (MF):
chromatin binding, zinc ion binding...
chromatin binding, zinc ion binding
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GO - Cellular component (CC):
nucleoplasm, nucleus, aggresome...
nucleoplasm, nucleus, aggresome
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tripartite motif containing 66
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Kaplan plot for TRIM66 in
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*NOTE: the Kaplan plots were collected from OncoLnc