INSRR
Entrez ID: 3645
Full name: insulin receptor related receptor
External links: HGNC UniprotKB Ensembl RefSeq COSMIC
Family: TK: InsR
Chromosomal location: 1q23.1
Substructure location: Gatekeeper: 1059 A-loop: 1132...1157 G-loop: [N/A] αC-helix: [N/A]
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INSRR
Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB....
Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB.
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GO - Biological processes (BP):
actin cytoskeleton reorganization, anatomical structure development, cellular response to alkaline pH, male sex determination, multicellular organism development, positive regulation of kinase activity, protein autophosphorylation, transmembrane receptor protein tyrosine kinase signaling pathway...
actin cytoskeleton reorganization, anatomical structure development, cellular response to alkaline pH, male sex determination, multicellular organism development, positive regulation of kinase activity, protein autophosphorylation, transmembrane receptor protein tyrosine kinase signaling pathway
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GO - Molecular function (MF):
ATP binding, insulin-activated receptor activity, insulin receptor substrate binding, phosphatidylinositol 3-kinase binding, transmembrane receptor protein tyrosine kinase activity...
ATP binding, insulin-activated receptor activity, insulin receptor substrate binding, phosphatidylinositol 3-kinase binding, transmembrane receptor protein tyrosine kinase activity
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GO - Cellular component (CC):
insulin receptor complex, integral component of plasma membrane, axon, receptor complex...
insulin receptor complex, integral component of plasma membrane, axon, receptor complex
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insulin receptor related receptor
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Kaplan plot for INSRR in
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*NOTE: the Kaplan plots were collected from OncoLnc