PHKG2
Entrez ID: 5261
Full name: phosphorylase kinase catalytic subunit gamma 2
External links: HGNC UniprotKB Ensembl RefSeq COSMIC
Family: CAMK: PHK
Chromosomal location: 16p11.2
Substructure location: Gatekeeper: 107 A-loop: 170...192 G-loop: [N/A] αC-helix: 64...84
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PHKG2
Catalytic subunit of the phosphorylase b kinase (PHK), which mediates the neural and hormonal regulation of glycogen breakdown (glycogenolysis) by phosphorylating and thereby activating glycogen phosphorylase. May regulate glycogeneolysis in the testis. In vitro, phosphorylates PYGM (By similarity)....
Catalytic subunit of the phosphorylase b kinase (PHK), which mediates the neural and hormonal regulation of glycogen breakdown (glycogenolysis) by phosphorylating and thereby activating glycogen phosphorylase. May regulate glycogeneolysis in the testis. In vitro, phosphorylates PYGM (By similarity).
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GO - Biological processes (BP):
generation of precursor metabolites and energy, glycogen biosynthetic process, glycogen catabolic process, glycogen metabolic process, positive regulation of glycogen catabolic process, protein phosphorylation...
generation of precursor metabolites and energy, glycogen biosynthetic process, glycogen catabolic process, glycogen metabolic process, positive regulation of glycogen catabolic process, protein phosphorylation
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GO - Molecular function (MF):
ATP binding, calmodulin binding, enzyme binding, phosphorylase kinase activity, protein serine/threonine kinase activity, tau-protein kinase activity...
ATP binding, calmodulin binding, enzyme binding, phosphorylase kinase activity, protein serine/threonine kinase activity, tau-protein kinase activity
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GO - Cellular component (CC):
cytosol, phosphorylase kinase complex...
cytosol, phosphorylase kinase complex
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phosphorylase kinase catalytic subunit gamma 2
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Kaplan plot for PHKG2 in
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*NOTE: the Kaplan plots were collected from OncoLnc