NPR2
Entrez ID: 4882
Full name: natriuretic peptide receptor 2
External links: HGNC UniprotKB Ensembl RefSeq COSMIC
Family: RGC: RGC
Chromosomal location: 9p13.3
Substructure location: Gatekeeper: 596 A-loop: [N/A] G-loop: [N/A] αC-helix: [N/A]
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NPR2
Receptor for the C-type natriuretic peptide NPPC/CNP hormone. Has guanylate cyclase activity upon binding of its ligand. May play a role in the regulation of skeletal growth....
Receptor for the C-type natriuretic peptide NPPC/CNP hormone. Has guanylate cyclase activity upon binding of its ligand. May play a role in the regulation of skeletal growth.
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GO - Biological processes (BP):
bone development, cellular response to granulocyte macrophage colony-stimulating factor stimulus, cGMP biosynthetic process, cGMP-mediated signaling, negative regulation of meiotic cell cycle, negative regulation of oocyte maturation, ossification, positive regulation of cGMP-mediated signaling, rec...
bone development, cellular response to granulocyte macrophage colony-stimulating factor stimulus, cGMP biosynthetic process, cGMP-mediated signaling, negative regulation of meiotic cell cycle, negative regulation of oocyte maturation, ossification, positive regulation of cGMP-mediated signaling, receptor guanylyl cyclase signaling pathway, regulation of blood pressure, regulation of cardiac conduction, reproductive process, signal transduction
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GO - Molecular function (MF):
ATP binding, GTP binding, guanylate cyclase activity, hormone binding, identical protein binding, natriuretic peptide receptor activity, peptide hormone binding, peptide receptor activity, protein kinase activity...
ATP binding, GTP binding, guanylate cyclase activity, hormone binding, identical protein binding, natriuretic peptide receptor activity, peptide hormone binding, peptide receptor activity, protein kinase activity
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GO - Cellular component (CC):
integral component of plasma membrane, plasma membrane...
integral component of plasma membrane, plasma membrane
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natriuretic peptide receptor 2
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*NOTE: the Kaplan plots were collected from OncoLnc